睡眠和肥胖神经科学关系

1. 睡眠障碍影响肥胖发生的研究发现；

1.1. 急性部分性睡眠剥夺增加动物体重；

Acute partial sleep deprivation due to environmental noise increases weight gain by reducing energy expenditure in rodents.

1.2. 一岁儿童的睡眠差异和肥胖发生相关；

Sleep differences in one-year-old children were related to obesity risks based on their parents' weight according to baseline longitudinal study data.

1.3. 睡眠和脂肪代谢之间存在相互作用关系；

Sleep Duration and Adiposity in Early Childhood: Evidence for Bidirectional Associations from the Born in Bradford Study.

1.4. 睡眠时间过少可能增加碳水化合物的摄入，并影响肥胖的风险；

Short Sleep Duration is Associated with Eating More Carbohydrates and Less Dietary Fat in Mexican American Children.

Is sleep education an effective tool for sleep improvement and minimizing metabolic disturbance and obesity in adolescents?

Lack of sleep as a contributor to obesity in adolescents: impacts on eating and activity behaviors.

1.5. 不吃早餐和睡眠不佳增加肥胖风险；

Skipping breakfast and poor sleep linked to childhood obesity, study finds.

1.6. 睡眠不足，运动过少和肥胖密切相关；

Excessive homework, inadequate sleep, physical inactivity and screen viewing time are major contributors to high paediatric obesity.

1.7. 睡眠缺乏可能诱导脂肪炎症和胰岛素抵抗从而增加肥胖发生风险；

Chronic Sleep Disruption Alters Gut Microbiota, Induces Systemic and Adipose Tissue Inflammation and Insulin Resistance in Mice.

1.8. 睡眠质量和时间和肥胖的发生密切相关；

Sleep quality and duration is related with diet and obesity in young

adolescent living in Sicily, Southern Italy.

Disturbances of sleep and circadian rhythms: novel risk factors for obesity.

Sleep Duration and Overweight/Obesity in Preschool-Aged Children: A Prospective Study of up to 48,922 Children of the Jiaxing Birth Cohort.

Sleep quality and obesity in young subjects: a meta-analysis.

Sleep Duration and Obesity in Adults: What Are the Connections?

Short sleep duration and obesity among children: A systematic review and meta-analysis of prospective studies.

1.9. 睡眠剥夺增加学龄前儿童的饮食；

Acute sleep restriction increases dietary intake in preschool-age children.

2.睡眠和饮食调控的神经环路重叠；

2.1. 食欲素神经元既调节饮食，也参与睡眠调节；

2.2. 剥夺饮食和剥夺睡眠都有相似的Orexin神经元突触反应活动；

2.3. 饮食和睡眠都受到日夜节律的影响；

2.4. 肥胖者Orexin A水平显著高于非肥胖者；

2.5. Orexin A增加摄食和体重；

2.6. 睡眠剥夺增加Orexin A水平；

REM sleep loss associated changes in orexin-A levels in discrete brain areas in rats.

Increased hypocretin-1 levels in cerebrospinal fluid after REM sleep deprivation.

2.7. 饮食、睡眠的调控神经环路相互重叠；

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