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Cell—研究发现一类独特的小胶可以限制阿尔茨海默病的进展
Abstract
Title and authors
Summary
1.Single-Cell RNA-Seq Reveals a Unique Microglia Type Associated with Alzheimer’s Disease
2.Disease-Associated Microglia Display Dynamics of Activation during AD Progression
3.DAM Are Localized Near the AD Plaques
4.DAM Are Phagocytic Cells Conserved in Human and Other Neurodegenerative Diseases
5.DAM Activation Is Initiated by a Trem2-Independent Pathway
6.DAM Are Regulated through a Two-Step Activation Mechanism
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