||
Nature neurosci——CADM1是调控体重和能量稳态的关键分子
Abstract
1.BMI risk SNPs associate with increased CADM1 and CADM2
expression in the hypothalamus of human subjects.
2.Induction of Cadm1 in excitatory neurons increases body weight.
3.Loss of Cadm1 in excitatory neurons affects body weight, energy homeostasis and thermogenesis.
4.Loss of neuronal Cadm1 protects from genetically and diet-induced obesity and insulin resistance.
5.Targeting Cadm1 expression in the hippocampus and hypothalamus reduces body weight.
经典文章回顾
你对老年性痴呆症到底懂多少?
喜欢我,关注我
拉到最上方标题下,点击上方蓝字关注
搜索公众号名称:神经科学临床和基础
也请你推荐给你身边的医学朋友,感谢你~
Archiver|手机版|科学网 ( 京ICP备07017567号-12 )
GMT+8, 2024-11-24 13:55
Powered by ScienceNet.cn
Copyright © 2007- 中国科学报社