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Nature cell biology——泛素化是蛋白酶体和自噬降解途径的共同信号
Title and authors
1.Substrate specificity of proteasome pathway Dsk2 and autophagy pathway Cue5 ubiquitin receptors
2.Role of ubiquitylation enzymes and ubiquitin chain types in substrate targeting by Dsk2 and Cue5.
3.Substrate binding properties of Dsk2 and Cue5 ubiquitin receptors.
4.Cue5 forms oligomers involving its CUE domain. (a) Selfinteraction of Cue5 but not Dsk2 ubiquitin receptors.
5.Synthetic receptors reveal requirements for proteasome/autophagy pathway choice.
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