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Neuron——隔区胆碱能神经调控觉醒过程中星胶NMDAR依赖的门控作用
Abstract
1. Daily Oscillations of D-Serine Availability Are Driven by Wakefulness
2.Wakefulness-Dependent Fluctuations of D-Serine Concentration In Vivo
3.Oscillations in NMDAR Occupancy Impact Learning and Memory
4.Inhibition of SNARE-Mediated Vesicular Release in Astrocytes Abolishes D-Serine Oscillations
5.Endogenous Cholinergic Signaling Controls D-Serine Availability across the 24 hr Period
6.Cholinergic Volume Transmission Elicits a Long-Lasting Increase of NMDAR Co-agonist Site Occupancy
7.Astrocyte-Specific a7nAChR Knockout Abolishes D-Serine Oscillations
8.Cholinergic Transmission Tunes the Gating of NMDARs through Astrocyte-Dependent D-Serine Release
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