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Science——Pcdh多群异质性为嗅觉环路发育所必需
Abstract
1.Distinct combinations of Pcdha, -β, and -γ isoforms are stochastically expressed in individual OSNs.
2.Multiple Pcdh gene clusters are required for normal OSN axonal arborization and the formation of normal protoglomeruli.
3.Uni-identity OSN axons fail to form glomeruli.
4.Uni-identity like-OSN axons fail to converge in the OB.
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