||
Background: Ms. Li entered the Ph.D. program in Institute of Neuroscience, Shanghai Institutes for Biological Science, Chinese Academy of Science in 2009. Her advisor is Dr.杜久林. She focuses on understanding the role of microglia and its interplay with neuronal activity in the zebra fish nervous system. She found that the resting microglia-neuron contact in turn reduces both the spontaneous and visually evoked activities of contacted neurons at single and populational neuron levels.
Shan Li Background: Ms. Li received her bachelor degree from China Agricultural University in 2007, and is conducting her Ph.D. research in the laboratory of Dr. Shao, Feng at the National Institute of Biological Science (NIBS)/China Agricultural University. Her research focuses on the function of a virulence factor called NleB from diarrhea-causing Enteropathogenic E. coli (EPEC). The mechanism of action of NleB identified from her work represents not only a new paradigm in bacterial counteracting host defenses but also a previously unappreciated posttranslational modification in eukaryotic signaling regulation. Jiaxuan Feng Background: Mr. Feng received his bachelor of medicine degree from Second Military Medical University in 2008, and is conducting his Ph.D. study under the direction of Dr. 李景平. He engaged in biomechanical study of aortic dissection. Lan Jiang Background: Mr. Jiang received his bachelor degree from Wuhan University in 2005, and is conducting his Ph.D. research in the laboratory of Dr. 吴仲义 at Beijng Institute of Genomics, Chinese Academy of Science. His has always been interested in the epigenetic reprogramming in several biological processes. Using zebra fish as a model system, Lan and co-worker took a joint effort in decoding the landscape of epigenetic reprogramming during the early development of zebra fish. With the large scale sequencing approach, they found that epigenetic information is used differently across zebra fish life history. While the maternal information is heavily used in early development, starting from midblastula (MBT) stage, the paternal epigenome begins to play the major role. Huan Yan Background: Mr. Yan received his BS degree from Wuhan University in 2008, and entered the Ph.D. program in National Institute of Biological Science (NIBS) / Peking University in 2010. Under the direction of Dr. Wenhui Li, he led his team to identify NTCP as a functional receptor for HBV and hepatitis delta virus (HDV), its satellite virus. Xiaoshan Shi Background: Mr. Shi entered the PhD program in Institute of Biochemistry and Cell Biology (IBCB), Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, where he studies under Dr.许琛琦 in 2011. The project he has been studying is the molecular mechanism of T-cell antigen receptor (TCR) triggering. 1) His work shows a new function of Ca2+ on the manipulation of membrane environment, which might has a general application to other signaling pathways. 2) He and his co-worker find the structural basis for Lck-CD3 interaction and demonstrate the functional importance of this interaction on T cell activation. Jun Lv Background: Mr. Lv received his Bachelor of Science degree from Beijing Normal University in 2009 and entered the Ph.D. program in Kunming Institute of Zoology, Chinese Academy of Science in 2011. His advisor is Dr. Wen Wang. For the past three years, he has been working on rice domestication and improvements using a genomic approach combining next generation sequencing (NGS) and bioinformatic analysis. He comes up with a novel idea of allele mining, which termed as ETAS (elite variety tag SNPs) strategy. Xinyang Song Background: Mr. Song received his BS from China Pharmaceutical University in 2007, and is conducting his Ph.D. study under the direction of Dr. Youcun Qian at Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Science. His Ph.D. thesis is to investigate the mechanisms by which interleukin-17 (IL-17) cytokine family functions in host defense system and autoimmunity. His work for the first time proves that IL-17RE is a receptor specific to IL-17C and has an essential role in host mucosal defense against infection. Xiong Ji Background: Mr. Ji received his bachelor degree from Wuhan University in 2008, and entered the Ph.D. program in the laboratory of Dr. 付向东 at Wuhan University in 2010. His work has been focused on a novel function of a typical splicing factor called SC35 in transcriptional activation. He discovered that the RNA binding protein also binds to gene promoters as part of the 7SK complex and that knockdown of the factor causes Pol II to become further paused near the transcription state site. This suggests that SC35 plays a critical role in transcription pause release. Kol Jia Yong Background: Ms. Yong has done her Ph. D. with Professor Dan Tenen in Cancer Science Institute (CSI) of Singapore. She graduated from National University of Singapore with biomedical major. She is among the first group of graduate students enrolled and trained in CSI. Her Ph. D work is a challenging and highly risky project that is beyond Tenen’s lab’s previous expertise and leading to a new direction on a stem cell factor, Sall4, in liver cancer development. In many ways, she drives this project independently and overcomes technical hurdles and finally makes some striking findings on Sall4, as an key factor involving liver cancer. Most interestingly her work showed an interesting epigenetic connection and revealed a possible therapeutic target for liver cancer.
|
Archiver|手机版|科学网 ( 京ICP备07017567号-12 )
GMT+8, 2024-10-19 22:12
Powered by ScienceNet.cn
Copyright © 2007- 中国科学报社