2017年12月12日PNAS在线文章，该文章为南方科技大学讲座教授郭红卫课题组发表，第一作者单位为南方科技大学和北京大学。文章讲述了EIN3/EIL1和RHD6/RSL1组成的关键转录复合体，在根毛发生和伸长的控制中起着重要的作用。

原题目为：

Ethylene promotes root hair growth through coordinated EIN3/EIL1 and RHD6/RSL1 activity in Arabidopsis

根毛是根表皮细胞的单细胞延伸，帮助植物增加水分和养分吸收，改善土壤固着，这两方面对全球公认的降低化肥用量，提高作物产量的目标都是至关重要的。以前的研究，在控制根毛发育中已经涉及到许多基因和植物激素。本研究揭示了乙烯促进根毛生长的分子机制，并鉴定出一个由EIN3/EIL1和RHD6/RSL1组成的转录复合体，是根毛起始和伸长的关键调节因子。由于乙烯介导各种根毛刺激的作用，这项工作也阐明了融合多种环境因素和内在信号调控植物器官发育的融合信号网络。

Root hairs are unicellular extensions of root epidermal cells that help plants increase water and nutrient uptake and improve soil anchorage, both of which are crucial for the globally recognized goal of yield improvement with reduced fertilizer use. Previous studies have implicated numerous genes and phytohormones in the control of root hair development. This work uncovers the molecular mechanism of ethylene (ET)-promoted root hair growth and identifies a transcriptional complex consisting of EIN3/EIL1 and RHD6/RSL1 as the key regulator of root hair initiation and elongation. As ET mediates the effects of various root hair stimuli, this work also elucidates a convergent signaling network that integrates diverse environmental cues and intrinsic signals to modulate plant organ development.

根毛是根表皮细胞的广泛结构，对于固着的植物来说，它对营养吸收，土壤固着和环境相互作用有重要作用。植物激素乙烯促进根毛生长，并且还具有介导刺激根毛细胞发育的不同信号的作用。然而，乙烯诱导的根毛生长的分子基础仍然知之甚少。在这里，我们研究显示， EIN3与一个已被研究的根毛细胞正调节子RHD6可以物理上的相互作用，这两个因子可以直接的共激活根毛长度决定基因RSL4，从而促进根毛伸长。转录组分析进一步揭示了调节对EIN3/EIL1和RHD6/RSL1的平行作用。EIN3/EIL1和RHD6/RSL1通过选择性的调节一些核心根毛基因，从而协调地增强根毛发起始。因此，本研究揭示了一个由EIN3/EIL1和RHD6/RSL1组成的关键转录复合体，在根毛发生和伸长的控制中起着重要的作用，并为环境信号和内在调节因子在植物器官发育调控中的整合，提供了分子框架。

Root hairs are an extensive structure of root epidermal cells and are critical for nutrient acquisition, soil anchorage, and environmental interactions in sessile plants. The phytohormone ethylene (ET) promotes root hair growth and also mediates the effects of different signals that stimulate hair cell development. However, the molecular basis of ET-induced root hair growth remains poorly understood. Here, we show that ET-activated transcription factor ETHYLENE-INSENSITIVE 3 (EIN3) physically interacts with ROOT HAIR DEFECTIVE 6 (RHD6), a well-documented positive regulator of hair cells, and that the two factors directly coactivate the hair length-determining gene RHD6-LIKE 4 (RSL4) to promote root hair elongation. Transcriptome analysis further revealed the parallel roles of the regulator pairs EIN3/EIL1 (EIN3-LIKE 1) and RHD6/RSL1 (RHD6-LIKE 1). EIN3/EIL1 and RHD6/RSL1 coordinately enhance root hair initiation by selectively regulating a subset of core root hair genes. Thus, our work reveals a key transcriptional complex consisting of EIN3/EIL1 and RHD6/RSL1 in the control of root hair initiation and elongation, and provides a molecular framework for the integration of environmental signals and intrinsic regulators in modulating plant organ development.

每日一词

unicellular

英[ˌju:nɪˈseljələ(r)]

美[ˌjunɪˈsɛljəlɚ]

adj. 单细胞的;