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转录阻遏物复合物FRS7-FRS12调控拟南芥的开花时间和生长

已有 2012 次阅读 2017-12-4 14:50 |系统分类:论文交流

本论文于2017年5月11日发表于NATURE COMMUNICATIONS,原文题目如下:

The transcriptional repressor complex FRS7-FRS12 regulates flowering time and growth in Arabidopsis


摘要:

为有效地适应环境变化,大多数生物体都有相应的系统。植物的生物钟与外部信号协同作用,并作出相应,以确定季节性的生长和开花时间。这里,两个拟南芥转录因子, FRS7和FRS12,是这些过程的负调控因子。这些蛋白质尤其在短日照条件下积累,并相互作用形成复合物。 FRS7和FRS12的功能丧失导致早开花,并且在短日照条件下有过长的下胚轴。我们通过分子分析证明FRS7和FRS12影响这些发育过程是部分的通过与GI 和PIF4启动子结合并抑制其表达来实现的,也会影响其下游信号靶标。我们的数据揭示了一个光周期调节开花和生长的分子机制,并为植物如何适应季节变化提供了见解。


Abstract:

Most living organisms developed systems to efficiently time environmental changes. The plant-clock acts in coordination with external signals to generate output responses determining seasonal growth and flowering time. Here, we show that two Arabidopsis thaliana transcription factors, FAR1 RELATED SEQUENCE 7 (FRS7) and FRS12, act as negative regulators of these processes. These proteins accumulate particularly in short-day conditions and interact to form a complex. Loss-of-function of FRS7 and FRS12 results in early flowering plants with overly elongated hypocotyls mainly in short days. We demonstrate by molecular analysis that FRS7 and FRS12 affect these developmental processes in part by binding to the promoters and repressing the expression of GIGANTEA and PHYTOCHROME INTERACTING FACTOR 4 as well as several of their downstream signalling targets. Our data reveal a molecular machinery that controls the photoperiodic regulation of flowering and growth and offer insight into how plants adapt to seasonal changes.



每日一词

diurnal

英[daɪˈɜ:nl]

美[daɪˈɜ:rnl]

adj. 白天的; 每日的; 占用一天的; 只活一天的;

[例句]The diurnal cycle in circulation and cloudiness over the Subtropical Southeast pacific: a modeling study.

副热带东南太平洋环流和云量的日循环:模拟研究。





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