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▲ Vol 10 Issue 46 | 20 October, 2024
数据与智能驱动的前沿组学及分析技术
赵方庆, 崔庆华, 何顺民, 杜茁
组学分析技术作为现代生命科学的重要工具,正在推动研究者们对生物系统进行全面的解析。通过基因组学、蛋白质组学、代谢组学等多个学科的协同研究,人们能够从多维角度了解生命遗传物质的结构、功能和动态变化。组学分析技术不仅提供了高通量的数据获取手段,还为疾病机制解析、药物研发和个性化医学奠定了基础。随着大数据和人工智能的引入,组学数据的处理和分析能力得到了极大提升,使得对复杂生物系统的研究更加精确、全面,推动了生命科学从理论到应用的转变。本期“组学分析技术专刊”汇总展示了近年来该领域中的最新进展和成果。封面图以DNA双螺旋为主体,辅以蛋白质、分析工具和数据等元素,展示了组学研究领域多元化的研究内容和技术手段。
http://www.chinagene.cn/CN/volumn/volumn_395.shtml
▲ Vol 17 Issue 20 | 21 October, 2024
Bionic Capsule Lithium-Ion Battery Anodes for Efficiently Inhibiting Volume Expansion
Zhenhai Gao, Shun Rao, Junjun Wang, Deping Wang, Tianyao Zhang, Xinbo Feng, Yuanhang Liu, Jiawei Shi, Yao Xue, Weifeng Li, Lili Wang, Changru Rong, Yupeng Chen
Magnetite (Fe3O4) has a large theoretical reversible capacity and rich Earth abundance, making it a promising anode material for LIBs. However, it suffers from drastic volume changes during the lithiation process, which lead to poor cycle stability and low-rate performance. Taking inspiration from how plant cells mitigate excessive water uptake/loss through their cell walls to preserve the structural integrity of cells, in this work Fe3O4@PMMA multicore capsules were designed as a kind of anode material inhibiting volume expansion to promote industrial applications. More information can be found in the Rese arch Article by W. Li, L. Wang, C. Rong, Y. Chen and co-workers.
https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cssc.202482001
▲ Vol 96 Issue 42 | 22 October, 2024
Quantitatively Tracking the Speciation and Dynamics of Selenium Nanoparticles in Rice Plants
Xiao-Xia Zhou, Quanzhi Xiao, Kena Zhang, Yan Gao, Jie Zhang, Liping Fang, Bing Yan, Fangbai Li
The uptake, translocation, and transformation of engineered nanoparticles (ENPs) in plants present significant challenges due to the lack of effective determination methods. This is especially true for selenium nanoparticles (SeNPs), which hold promise for Se-biofortified agriculture and exhibit dynamic behaviors within plant system. Herein, we proposed a novel approach that incorporates enzymic digestion and membrane filtration to selectively extract SeNPs and dissolved Se from plant tissues, employing rice (Oryza sativa) plant as a model. Subsequently, the SeNPs retained on the membrane were quantified using inductively coupled plasma mass spectrometry (ICPMS), while the dissolved Se in the filtrate, including selenite (Se(IV)), selenate (Se(VI)), and seleno amino acid, were analyzed by liquid chromatography coupled with ICPMS (LC-ICPMS). Recoveries of 83.5–91.4% for SeNPs and 73.6–99.4% for dissolved Se at a spiking level of 8 μg/g in quality control samples were obtained. With the established method, it was discovered that SeNPs taken up by rice leaves can transform into Se (IV) and organic Se, and all the Se species could be translocated downward, but only Se (IV) and SeNPs could be excreted through the roots. These findings provide valuable insights into the fate of SeNPs in plants and their related biological responses.
https://pubs.acs.org/doi/10.1021/acs.analchem.4c04032
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