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2023年10月嘲风作品集（一）

已有 1116 次阅读 2024-1-22 16:30 |个人分类:作品发表|系统分类:论文交流

▲ Vol 02 Issue 04 | October , 2023

Bimetallic synergistic Pd-Pt icosahedra as highly active peroxidase-like mimics for colorimetric analysis

Xiaoxue Zhao, Zhe Li, Shu'na Wang, Zhenfeng Yuan, Yizhong Lu

Thanks to the synergistic effect, the bimetallic catalysts show better catalytic activity than the single metal catalysts and become a focus of research in heterogeneous catalysis. In this study, we successfully prepared Pd-Pt icosahedra which show high peroxidase-like activity under the synergistic effects of Pd and Pt. Vmax of the Pd-Pt icosahedra was significantly enhanced by 1.66 times for 3,3’,5,5’-tetramethylbenzidine (TMB) as the substrate and 1.23 times for H2O2 as the substrate, compared to that of the Pd icosahedra alone. By harnessing the superior peroxidase-like activity of Pd-Pt icosahedra, we successfully utilized Pd-Pt icosahedral nanozymes in various biological analyses based on colorimetry. In most cases, using a Pd-Pt icosahedra/H2O2/TMB system, glucose, glutathione (GSH), acid phosphatase (ACP), and alkaline phosphatase (ALP) were detected over a wide range of 0.05∼0.20 mM, 0∼20 mM, 0∼10 U/L and 0∼12 U/L. In this study, we prepared a novel bimetallic nanozyme that exhibited excellent peroxidase-like activity owing to the bimetallic synergistic effect, thus demonstrating the promising potential of Pd-Pt icosahedra in the field of bioanalysis.

https://www.sciencedirect.com/science/article/pii/S2772571523000335

▲ Vol 57 Issue 39 | 03 October , 2023

Unexpected Dioxin Formation During Digestion of Soil with Oxidizing Acids

Wenjing Xie, Wenjuan Li, Pu Wang, Yanfen Hao, Bolei Chen, Ligang Hu, Thanh Wang, Qinghua Zhang, Yong Liang, and Guibin Jiang

Dioxins, such as polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDD/Fs), are among the most toxic unintentionally produced persistent organic pollutants, and their emission is of great concern. Herein, we discovered abundant dioxin formation in soil and various organic carbon-containing matrices after digestion with aqua regia. Σ17PCDD/Fs concentrations were in the range of 66.6–142,834 pg/g dw (5.6–17,021 pg WHO2005-TEQ/g dw) in 19 soil samples after digestion with aqua regia for 6 h. Σ17PCDD/Fs concentration was significantly and positively correlated with soil organic carbon content (R2 = 0.89; p < 0.01). Compared with cellulose and lignin, humic acid served as an important organic matter component that was converted to PCDD/Fs during soil digestion. Strong oxidation and production of reactive chlorine by aqua regia may be the key factors in the formation of PCDD/Fs. The yearly emission of PCDD/Fs due to digestion with strong acids by the inspection and testing industry was estimated to be 83.8 g TEQ in China in 2021 based on the highest level, which was ∼0.9% of the total dioxin inventory in China. Great attention should be paid to unexpected dioxin formation during digestion processes considering the potential risk of release from laboratories and enterprises.

https://pubs.acs.org/doi/10.1021/acs.est.3c03682

▲ Vol 33 Issue 40 | 02 October , 2023

Electronic Interpretation of Interlayer Energy Landscape in Layered Materials

Xin Zhang, Junhui Sun, Shiyu Du, Hao Li, Linmao Qian

Interlayer Energy Landscape

In article number 2301402, Junhui Sun and co-workers use the diverse prevailing definitions of electronic coupling to evaluate their rationality in motivating interlayer sliding energy landscape in layered materials. It is found that the evolution of charge redistribution in dynamic contact enables to quantify interlayer sliding energy landscape, different from the previous belief of nonuniform charge distribution, or the charge redistribution in the interface region.

https://onlinelibrary.wiley.com/doi/10.1002/adfm.202370238

▲ Vol 10 Issue 10 | 01 October , 2023

Surface topography of nanoplastics modulates their internalization and toxicity in liver cells

Neng Yan, Yuhuai Wang, Tin Yan Wong, Yubing Hu, Huo Xu, Parodi Alessandro, Ke Pan, Jingjing Liu, Henry Lam, Ben Zhong Tang and Jianbo Shi

Though hepatotoxicity induced by the ubiquitous and potentially ingested nanoplastics (NPs) has been extensively studied, limited attention has been given to the role of NPs' surface topography. Since these ingested NPs pass through the human digestive system (HDS) before reaching the liver, their surface properties are altered, which affects their interactions with the organ. Herein, we prepared two different-sized aggregation-induced emission fluorogen-incorporated NPs (AIE-NPs) with diverse surface roughness by exposing NPs to the HDS for different durations. The HDS environment could effectively alter the surface roughness of the AIE-NPs, leading to an extended specific surface area and decreased hydrophobicity. Besides, roughening the NPs' surface facilitated their cellular internalization efficiency, mainly mediated by the specific surface area, which has been confirmed in vivo in a zebrafish model. After internalization, all these investigated AIE-NPs were consistently localized in lysosomes (Pearson's correlation coefficient > 0.8), suggesting that the surface roughness had negligible influence on their intracellular distribution pattern. The AIE-NPs with the rougher surface contributed to lysosomal alkalization and potentially caused lysosomal autophagy. Furthermore, exposure to AIE-NPs triggered reactive oxygen species (ROS) production, mitochondrial glutathione (mGSH) depletion and mitochondria dysfunction. The roughest AIE-NPs displayed the strongest cytotoxicity and sequentially led to cell apoptosis. Overall, this study highlighted the critical role of NP nanoscale surface topography, strengthening the understanding and assessment of NP toxicology.

https://pubs.rsc.org/en/content/articlelanding/2023/en/d3en00347g

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