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#编者信息
熊荣川
明湖实验室
xiongrongchuan@126.com
http://blog.sciencenet.cn/u/Bearjazz
These results imply that, early in their evolutionary history, duplicate genes tend to be under moderate selective constraints with the rate of amino acid substitution averaging about 43% of the neutral expectation. The efficiency of purifying selection subsequently increases approximately 10-fold, to the point at which only about 5% of amino acid–changing mutations are able to rise to fixation. | 这些结果表明,重复基因在其进化史的早期,往往处于中等选择性的约束下,氨基酸替代率平均约为43%,接近中性预期。纯化选择的效率随后增加约10倍,到只有约5%的改变氨基酸的突变能够被固定的程度。 |
Lynch, M. The Evolutionary Fate and Consequences of Duplicate Genes[J]. Science, 2000, 290(5494):1151-1155.
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