提出观点:

1 Dickson, S.P., Wang, K., Krantz, I., Hakonarson, H., and Goldstein, D.B. Rare Variants Create Synthetic Genome-Wide Associations. PLoS Biol 8, e1000294.Rare Variants Create Synthetic Genome-Wide Associations.pdf
反对意见:

2 Anderson, C.A., Soranzo, N., Zeggini, E., and Barrett, J.C. Synthetic Associations Are Unlikely to Account for Many Common Disease Genome-Wide Association Signals. PLoS Biol 9, e1000580.Synthetic Associations Are Unlikely to Account for.pdf
3 Wray, N.R., Purcell, S.M., and Visscher, P.M. Synthetic Associations Created by Rare Variants Do Not Explain Most GWAS Results. PLoS Biol 9, e1000579.Synthetic Associations Created by Rare.pdf

再次说明:

4 Goldstein, D.B. The Importance of Synthetic Associations Will Only Be Resolved Empirically. PLoS Biol 9, e1001008.The Importance of Synthetic Associations Will Only.pdf

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