就是这个词了copy number variation,几年前注意到在人类遗传学研究中比较关注这个.当然这东西肯定不会是人类的特例,所以一直比较留意植物中的研究.因为这是新生事物,它有很大的发展潜力.今天抓住了拟南芥中的一个该方向的研究.Copy Number Variation Shapes Genome Diversity in Arabidopsis Over Immediate Family Generational ScalesCopy Number Variation

      对这篇文章除了CNV外,其结果能支持这个观点:在特定的环境条件下,植物基因组会发生改变(发生了改变,所以才产生了CNV).这好象也不是什么新鲜观点了,水稻组培条件下能发生转座子的激活产生新的突变.我感觉这个结果可能还有进一步发挥的余地.

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实验设计特点:同一个生态型(Columbia-0),在不同的环境(grown under different temperature (16 and 28
C) regimes and stress regimes (salicylic acid [SA] spray))(对照:正常种植,温度22度).观察点:是否存在gene CNV

结论:the genome of A. thaliana displayed unexpectedly high rates of physical change by CNV among closely
related lineages, affecting not tens but hundreds of genes between individuals separated by only five generations.

未解之迷:A mechanism by which stress is sensed and transferred to stimulate CNV (via recombination?)
remains unclear.(机制不明,但stress能刺激CNV是明确的).

这东西会不会有育种价值?

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     通过这篇文章知道,这也不是植物中的第1篇CNV了,2009年玉米中有1篇

Maize Inbreds Exhibit High Levels of Copy Number Variation (CNV) and Presence/Absence Variation (PAV) in
Genome Content

Maize

    关注这东西有什么意义?看文章的结果(第1篇)Results support a model whereby segmental
CNV and the genes encoded within these regions contribute to adaptive capacity of plants through natural genome variation.简单来说是通过CNV来适应环境,或者进一步,有的重要农艺性状的控制可能和CNV有关.如果是图位克隆,是CNV性状,会发生什么情况?

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什么是CNV?CNVs are microduplications and deletions, as opposed to wholegenome duplications

Population resequencing reveals local adaptation of Arabidopsis lyrata to serpentine soils

resequencing(这篇文章里提到CNV,我对它印象很深,但今晚把它抓出来到没那么容易)

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Distribution, functional impact, and origin mechanisms of copy number variation in the barley genome 
Muñoz-Amatriaín M, Eichten SR, Wicker T, Richmond TA, Mascher M, Steuernagel B, Scholz U, Ariyadasa R, Spannagl M, Nussbaumer T, Mayer KF, Taudien S, Platzer M, Jeddeloh JA, Springer NM, Muehlbauer GJ, Stein N