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2023年11月24日,Elsevier 宣布旗下知名期刊《Cell Reports Physical Science》在线发表了云南师范大学化学化工学院高层次柔性引进人才、厦门大学化学化工学院教授叶龙武教授团队的最新研究成果《Catalytic asymmetric reaction of isoxazoles and benzisoxazoles》.云南师范大学化学化工学院高层次朱欣祺为第一作者,叶龙武和朱欣祺为共同通讯作者。
Isoxazoles and their derivatives have been verified to be versatile building blocks and crucial intermediates for the synthesis of a range of useful N-containing molecules, especially valuable N-heterocycles. However, the catalytic asymmetric reaction of isoxazole derivatives has been rarely explored, and there is no systematic summary to date. In this perspective, we summarize the recent advances in the catalytic asymmetric reaction of isoxazoles and benzisoxazoles according to different types of reactions: (1) transition-metal-catalyzed asymmetric ring contraction of isoxazoles, (2) copper-catalyzed asymmetric hydroamination of alkenes and alkynes with benzisoxazoles, and (3) transition-metal-catalyzed asymmetric formal annulations of isoxazoles and benzisoxazoles. Finally, we propose the remaining challenges and opportunities for future breakthroughs in this area.
https://www.sciencedirect.com/science/article/pii/S266638642300468X
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h瑞士洛桑联邦理工学院(EPFL)博士后朱欣祺加盟云南师范大学
https://lwye.xmu.edu.cn/Prof__Longwu_Ye/ylw_bs.htm
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