卿志和，云南师范大学生命科学学院2005级本科生，优青，教授 博导  ，现任长沙理工大学化工学院院长

简介：卿志和，教授，博士生导师，国家优青、湖南省优青，“细胞化学”湖南省重点实验室常务副主任，“健康化学”湖南省普通高等学校科技创新团队带头人，长沙理工大学化学化工学院副院长、“湖湘学者”拔尖人才。已主持国家自然科学基金优青项目、面上项目、湖南省自科优青项目、企业技术服务项目等10余项，在 PNAS、 Angew. Chem.、Nano Today、Chem. Sci.、Anal. Chem. CCS Chem.等国内外高水平期刊上发表学术论文78余篇，授权专利10余件，获得湖南省自然科学一等奖等奖励。担任Chinese Chemical Letters、The Innovation、《分析试验室》等国内外权威期刊的编委或青年编委。

教育和工作经历

现任长沙理工大学化学化工学院副院长

2018/1-至今，长沙理工大学化学与食品工程学院，教学科研，副教授

2015/4-2017/12，长沙理工大学化学与食品工程学院，教学科研，讲师

2011/9–2014/12，湖南大学化学化工学院，分析化学，博士

2009/9–2011/7，湖南大学生物医学工程中心，生物医学工程，硕士

2005/9–2009/7，云南师范大学生命科学学院，生物科学，学士

【主要研究领域】

[1] 核酸-金属作用机制及生物传感

[2] 药物靶向控制释放

[3] 食品安全与环境监测

[1] Yibo Zhou, Zhengxuan Gu, Changhui Liu, Sheng Yang,* Xiaofei Ma, Qiaoshu Chen, Yanli Lei, Ke Quan, Juewen Liu, Zhihe Qing,* Ronghua Yang*. A Polymeric Nanobeacon for Revealing Hydrogen Polysulfides Fluctuation during Fertilization and Embryonic Development. Angew. Chem. Int. Ed. 2022, DOI: 10.1002/anie.202114504.

[2] Zhen Zou, Libei He, Xiangxi Deng, Huangxiang Wang, Ziyun Huang, Qian Xue, Zhihe Qing*, Yanli Lei, Ronghua Yang*, and Juewen Liu. Zn2+-Coordination-Driven RNAAssembly with Retained Integrity and Biological Functions. Angew. Chem. Int. Ed. 2021, 60, 22970–22976.

[3] Lifang Chen, Shuohui Xing, Yanli Lei, Qiaoshu Chen, Zhen Zou, Ke Quan, Zhihe Qing*, Juewen Liu, and Ronghua Yang*. A Glucose-Powered Activatable Nanozyme Breaking pH and H2O2 Limitations for Treating Diabetic Infections. Angew. Chem. Int. Ed. 2021, 60, 23534–23539.

[4] Zhihe Qing, Guoyan Luo, Shuohui Xing, Zhen Zou, Yanli Lei, Juewen Liu*, Ronghua Yang*. Pt-S Bond Mediated Nanoflares for High-Fidelity Intracellular Applications by Avoiding Thiol Cleavage. Angew. Chem. Int. Ed.2020, 59, 14044 –14048.

[5] Zhihe Qing*, Jinlei Hu, Jingyuan Xu, Zhen Zou, Yanli Lei, Taiping Qing, Ronghua Yang*. An intramolecular catalytic hairpin assembly on a DNA tetrahedron for mRNA imaging in living cells: improving reaction kinetics and signal stability. Chem. Sci. 2020, 11, 1985–1990.

[6] Zhihe Qing*, Jingyuan Xu, Jing Zheng, Lei He, Zhen Zou, Sheng Yang, Weihong Tan, Ronghua Yang*. In Situ Amplification-Based Imaging of RNA in Living Cells. Angew. Chem. Int. Ed. 2019, 58, 11574–

Zhihe Qing, Xiaoxiao He, Dinggeng He, Kemin Wang, Fengzhou Xu, Taiping Qing, Xue Yang. Poly(thymine)-templated selective formation of fluorescent copper nanoparticles. Angew. Chem., 2013, 52, 9719–9722. （国际top期刊，SCI 1区，第一作者）。

Zhihe Qing, Lixuan Zhu, Lina Hou, Zhen Zou, Sheng Yang, Ronghua Yang. A dsDNA-lighted fluorophore for monitoring protein-ligand interaction through binding-mediated DNA protection. Science China Chemistry, 2018, 61, 1630-1636. （SCI 2区，第一作者）。

Zhihe Qing, Lixuan Zhu, Xiaoxuan Li, Sheng Yang, Zhen Zou, Jingru Guo, Zhong Cao, and Ronghua Yang. A Target-Lighted dsDNA-Indicator for High-Performance Monitoring of Mercury Pollution and Its Antagonists Screening. Environment Science & Technology, 2017, 51, 11884−11890. （国际top期刊，SCI 1区，第一作者）。

Lixuan Zhu, Zhihe Qing, Lina Hou, Sheng Yang, Zhen Zou, Zhong Cao,and Ronghua Yang. Direct Detection of Nucleic Acid with Minimizing Background and Improving Sensitivity Based on a Conformation-Discriminating Indicator. ACS Sensors 2017, 2, 1198−1204（SCI 1区，通讯作者）。

Changhui Liu，Weiju Chen，Zhihe Qing，Jing Zheng，Yue Xiao，Sheng Yang，Lili Wang，Yinhui Li，Ronghua Yang，In Vivo Lighted Fluorescence via Fenton Reaction: A New Approach for Imaging of Hydrogen Peroxide in Living Systems，Analytical Chemistry, 2016, 88, 3998−4003.（国际top期刊，SCI 1区，通讯作者）。

Le Yang, Zhihe Qing, Changhui Liu, Qiao Tang, Jishan Li, Sheng Yang, Jing Zheng, Ronghua Yang, and Weihong Tan，Direct Fluorescent Detection of Blood Potassium by Ion-Selective Formation of Intermolecular GQuadruplex and Ligand Binding，Analytical Chemistry, 2016, 88, 9285−9292.（国际top期刊，SCI 1区，通讯作者）。

Zhihe Qing，Lixuan Zhu，Sheng Yang，Zhong Cao，Xiaoxiao He，Kemin Wang，Ronghua Yang，In situ formation of fluorescent copper nanoparticles for ultrafastzero-background Cu2+ detection and its toxicides screening，Biosensors and Bioelectronics，2016，78, 471-476.（国际top期刊，SCI 1区，第一作者）。

Zhihe Qing, Lina Hou, Le Yang, Lixuan Zhu, Sheng Yang, Jing Zheng, Ronghua Yang. A Reversible Nanolamp for Instantaneous Monitoring of Cyanide Based on an Elsner-like Reaction. Analytical Chemistry, 2016, 88, 9759−9765. （国际top期刊，SCI 1区，第一作者）。

Zhihe Qing, Xiaoxiao He, Taiping Qing, Kemin Wang, Hui Shi, Dinggeng He, Zhen Zou, Lvan Yan, Fengzhou Xu, Xiaosheng Ye, Zhengui Mao. Poly(thymine)-templated fluorescent copper nanoparticles for ultrasensitive label-free nuclease assay and its inhibitors screening. Analytical Chemistry, 2013, 85, 12138−12143. （国际top期刊，SCI 1区，第一作者）。

Zhihe Qing, Xiaoxiao He, Jin Huang, Kemin Wang, Zhen Zou, Taiping Qing, Zhengui Mao, Hui Shi, Dinggeng He. Target-catalyzed dynamic assembly-based pyrene excimer switching for enzyme-free nucleic acid amplified detection. Analytical Chemistry, 2014, 86, 4934−4939. （国际top期刊，SCI 1区，第一作者）。

Zhihe Qing, Zhengui Mao, Taiping Qing, Xiaoxiao He, Zhen Zou, Dinggeng He, Hui Shi, Jin Huang, Jianbo Liu, and Kemin Wang. Visual and portable strategy for copper (II) detection based on a striplike poly(thymine)-caged and microwell-printed hydrogel. Analytical Chemistry, 2014, 86, 11263−11268. （国际top期刊，SCI 1区，第一作者）。

Zhihe Qing, Taiping Qing, Zhengui Mao, Xiaoxiao He, Kemin Wang, Zhen Zou, Hui Shi and Dinggeng He. dsDNA-specific fluorescent copper nanoparticles as a “green” nano-dye for polymerization-mediated biochemical analysis. Chemical Communications, 2014, 50, 12746–12748. （国际top期刊，SCI 1区，第一作者）。

Zhengui Mao, Zhihe Qing, Taiping Qing, Fengzhou Xu, Li Wen, Xiaoxiao He, Dinggeng He, Hui Shi, and Kemin Wang. Poly(thymine)-Templated Copper Nanoparticles as a Fluorescent Indicator for Hydrogen Peroxide and Oxidase-Based Biosensing. Analytical Chemistry，2015, 85, 7454-7460. （国际top期刊，SCI 1区，共同第一作者）。