1.B7-H1 agonists could prevent disseminated inflammation by desensitizing cell susceptibility to cytotoxic T-cells
 Yu,Weiwei;Chen,Ling;Guo,Sizheng;
ONCOIMMUNOLOGY 7 11 NOV 2 2018
2.A Paradigm Shift in Cancer Immunotherapy From Enhancement to Normalization
 Sanmamed,Miguel F.;Chen,Lieping
CELL 175 2 313-326 OCT 4 2018

3.B7-H4 Modulates Regulatory CD4(+) T Cell Induction and Function via Ligation of a Semaphorin 3a/Plexin A4/Neuropilin-1 Complex
 Podojil,Joseph R.;Chiang,Ming-Yi;Ifergan,Igal;
JOURNAL OF IMMUNOLOGY 201 3 897-907 AUG 1 2018

4.Defining and Understanding Adaptive Resistance in Cancer Immunotherapy
 Kim,Tae Kon;Herbst,Roy S.;Chen,Lieping
TRENDS IN IMMUNOLOGY 39 8 624-631 AUG 2018

5.B7-H1 maintains the polyclonal T cell response by protecting dendritic cells from cytotoxic T lymphocyte destruction (vol 115,pg 3126,2018)
 Chen,Ling;Azuma,Takeshi;Yu,Weiwei;
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 115 16 E3857-E3857 APR 17 2018

6.Spatially Resolved and Quantitative Analysis of VISTA/PD-1H as a Novel Immunotherapy Target in Human Non-Small Cell Lung Cancer
 Villarroel-Espindola,Franz;Yu,Xiaoqing;Datar,Ila;
CLINICAL CANCER RESEARCH 24 7 1562-1573 APR 1 2018
 2 

7.RNA deconvolution reveals distinctive immunogenetic landscapes in Nf2 and non-Nf2 meningiomas
 Yeung,Jacky;Harmanci,Akdes;Omay,Sacit;
JOURNAL OF NEUROSURGERY 128 4 13-13 512 APR 2018

8.B7-H1 maintains the polyclonal T cell response by protecting dendritic cells from cytotoxic T lymphocyte destruction
 Chen,Ling;Azuma,Takeshi;Yu,Weiwei;
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 115 12 3126-3131 MAR 20 2018
 4 
9.DKK2 imparts tumor immunity evasion through beta-catenin-independent suppression of cytotoxic immune-cell activation
 Xiao,Qian;Wu,Jibo;Wang,Wei-Jia;
NATURE MEDICINE 24 3 262- MAR 2018
 4 
10.Human Semaphorin-4A drives Th2 responses by binding to receptor ILT-4
 Lu,Ning;Li,Ying;Zhang,Zhiqiang;
NATURE COMMUNICATIONS 9
11.S100A4 blockage alleviates agonistic anti-CD137 antibody-induced liver pathology without disruption of antitumor immunity
 Zhang,Jinhua;Song,Kun;Wang,Jun;
ONCOIMMUNOLOGY 7 4 e1296996 2018

12.PD-1H (VISTA) Induces Immune Evasion in Acute Myeloid Leukemia
 Kim,Tae Kon;Han,Xue;Wang,Jun;
BLOOD 130 1 2658 DEC 7 2017
13.Granulocytic myeloid-derived suppressor cells suppress virus-specific CD8(+) T cell responses during acute Friend retrovirus infection
 Drabczyk-Pluta,Malgorzata;Werner,Tanja;Hoffmann,Daniel;
RETROVIROLOGY 14 42 AUG 23 2017
 3 
14.PD-L1 Studies Across Tumor Types,Its Differential Expression and Predictive Value in Patients Treated with Immune Checkpoint Inhibitors
 Kluger,Harriet M.;Zito,Christopher R.;Turcu,Gabriela;
CLINICAL CANCER RESEARCH 23 15 4270-4279 AUG 1 2017
 19 
15. Programmed death one homolog maintains the pool size of regulatory T cells by promoting their differentiation and stability
 Wang,Qi;He,Jianwei;Flies,Dallas B.;
SCIENTIFIC REPORTS 7 6086 JUL 20 2017
 2 
16.PHY906(YIV-906),an adjuvant based on a 1800-year-old Chinese medicine,enhanced the anti-tumor activity of Immune checkpoint blockade therapy anti-PDL1,anti-PD1,anti-PD1/CTLA4 against melanoma
 Lam,Wing;Jiang,Zaoli;Han,Xue;
 CANCER RESEARCH 77 13 5584 JUL 2017
17.Acquired Resistance to Programmed Death-1 Axis Inhibitors in Non-Small Cell Lung Cancer (NSCLC)
 Choi,Jungmin;Sowell,Ryan;Truini,Anna;
JOURNAL OF THORACIC ONCOLOGY 12 1 S S1331-S1332 P3.02c-088 JAN 2017
18.Differential Expression and Significance of PD-L1,IDO-1,and B7-H4 in Human Lung Cancer
 Schalper,Kurt A.;Carvajal-Hausdorf,Daniel;McLaughlin,Joseph;
CLINICAL CANCER RESEARCH 23 2 370-378 JAN 2017
 5 
19.Classification of Advanced Human Cancers Based on Tumor Immunity in the MicroEnvironment (TIME) for Cancer Immunotherapy
 Zhang,Yu;Chen,Lieping
JAMA ONCOLOGY 2 11 1403-1404 NOV 1 2016
 15 
20.
Immunological prognostic factors in stage III melanomas
 Roberti,Maria Paula;Jacquelot,Nicolas;Enot,David P.;
JOURNAL OF TRANSLATIONAL MEDICINE 14 1 O14 JUL 25 2016
21.Immunophenotyping of Stage III Melanoma Reveals Parameters Associated with Patient Prognosis
 Jacquelot,Nicolas;Roberti,Maria Paula;Enot,David P.;
JOURNAL OF INVESTIGATIVE DERMATOLOGY 136 5 994-1001 MAY 2016
 8 
22.Neuron-specific SALM5 limits inflammation in the CNS via its interaction with HVEM
 Zhu,Yuwen;Yao,Sheng;Augustine,Mathew M.;
SCIENCE ADVANCES 2 4 UNSP e1500637 APR 2016
 4 
23.PD-L1 (B7-H1) and PD-1 pathway blockade for cancer therapy Mechanisms,response biomarkers,and combinations
 Zou,Weiping;Wolchok,Jedd D.;Chen,Lieping
SCIENCE TRANSLATIONAL MEDICINE 8 328 328rv4 MAR 2 2016
 327 
24.A monoclonal antibody against KCNK9 K+ channel extracellular domain inhibits tumour growth and metastasis
 Sun,Han;Luo,Liqun;Lal,Bachchu;
NATURE COMMUNICATIONS 7 10339 FEB 2016
 9 
25.PD-1 upregulated on regulatory T cells during chronic virus infection enhances the suppression of CD8(+) T cell immune response via the interaction with PD-L1 expressed on CD8(+) T cells (vol 194,pg 5801,2015)
 Park,H. J.;Park,J. S.;Jeong,Y. H.;
JOURNAL OF IMMUNOLOGY 195 12 5841-5842 DEC 15 2015
 5 
26.Expression of the Novel Costimulatory Molecule B7-H5 in Pancreatic Cancer
 Byers,Joshua T.;Paniccia,Alessandro;Kaplan,Jeffrey;
ANNALS OF SURGICAL ONCOLOGY 22 3 S1574-S1579 DEC 2015
 7 
27.PD-L1 Expression on Retrovirus-Infected Cells Mediates Immune Escape from CD8(+) T Cell Killing
 Akhmetzyanova,Ilseyar;Drabczyk,Malgorzata;Neff,C. Preston;
PLOS PATHOGENS 11 10 e1005224 OCT 2015
 25 
28.A big role in tumor immune microenvironment of a small non-coding RNA microRNA-200
 Chen,Limo;Goswami,Sangeeta;Yi,Xiaohui;
CANCER IMMUNOLOGY RESEARCH 3 10 S B67 OCT 2015
29.Characterization of tumor infiltrating lymphocytes in paired primary and metastatic renal cell carcinoma specimens
 Baine,Marina K.;Turcu,Gabriela;Zito,Christopher R.;
ONCOTARGET 6 28 24990-25002 SEP 22 2015
 12 
30.Anti-PD-1/PD-L1 therapy of human cancer past,present,and future
 Chen,Lieping;Han,Xue
JOURNAL OF CLINICAL INVESTIGATION 125 9 3384-3391 SEP 2015
 258 
31.Characterization of PD-L1 Expression and Associated T-cell Infiltrates in Metastatic Melanoma Samples from Variable Anatomic Sites
 Kluger,Harriet M.;Zito,Christopher R.;Barr,Meaghan L.;
CLINICAL CANCER RESEARCH 21 13 3052-3060 JUL 1 2015
 64 
32.Focusing and sustaining the antitumor CTL effector killer response by agonist anti-CD137 mAb
 Weigelin,Bettina;Bolanos,Elixabet;Teijeira,Alvaro;
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 112 24 7551-7556 JUN 16 2015
 28 
33.PD-1 Upregulated on Regulatory T Cells during Chronic Virus Infection Enhances the Suppression of CD8(+) T Cell Immune Response via the Interaction with PD-L1 Expressed on CD8(+) T Cells
 Park,Hyo Jin;Park,Joon Seok;Jeong,Yun Hee;
JOURNAL OF IMMUNOLOGY 194 12 5801-5811 JUN 15 2015
 51 
34.B7-H3 Promotes Pathogenesis of Autoimmune Disease and Inflammation by Regulating the Activity of Different T Cell Subsets
 Luo,Liqun;Zhu,Gefeng;Xu,Haiying;
PLOS ONE 10 6 e0130126 JUN 11 2015
 11 
35.Mechanistic Assessment of PD-1H Coinhibitory Receptor-Induced T Cell Tolerance to Allogeneic Antigens
 Flies,Dallas B.;Higuchi,Tomoe;Chen,Lieping
JOURNAL OF IMMUNOLOGY 194 11 5294-5304 JUN 1 2015
 20 
36.PD-L1,PD-1,and CTLA-4 as prognostic biomarkers in resected non-small cell lung cancer.
 Owonikoko,Taofeek Kunle;Kowalski,Jeanne;Kim,Sungjin;
JOURNAL OF CLINICAL ONCOLOGY 33 15 S 7551 MAY 20 201
 2 

37.PD-1+CD28H+selectively identifies for superior tumor-reactive T lymphocytes in pancreatic cancer
 Zhu,Yuwen;Koenig,Michelle;Byers,Joshua;
JOURNAL OF IMMUNOLOGY 194 1 TUM7P.1013 MAY 1 2015

38.Immunomodulation Therapy goes to Tumor Site
 Chen,Lieping
FASEB JOURNAL 29 1 486.3 APR 2015

39.PD-1 Suppresses Protective Immunity to Streptococcus pneumoniae through a B Cell-Intrinsic Mechanism
 McKay,Jerome T.;Egan,Ryan P.;Yammani,Rama D.;
JOURNAL OF IMMUNOLOGY 194 5 2289-2299 MAR 1 2015
 9 
40.B7H1/CD80 Interaction Augments PD-1-Dependent T Cell Apoptosis and Ameliorates Graft-versus-Host Disease
 Deng,Ruishu;Cassady,Kaniel;Li,Xiaofan;
JOURNAL OF IMMUNOLOGY 194 2 560-574 JAN 15 2015
 27 
41.Consensus nomenclature for CD8(+) T cell phenotypes in cancer
 Apetoh,Lionel;Smyth,Mark J.;Drake,Charles G.;
ONCOIMMUNOLOGY 4 4 e998538 2015
 43 
42.Intermittent chemotherapy can retain the therapeutic potential of anti-CD137 antibody during the late tumor-bearing state
 Tongu,Miki;Harashima,Nanae;Tamada,Koji;
CANCER SCIENCE 106 1 9-17 JAN 2015
 3 
43.B7H1/B7.1 Interaction Alleviate Acute Gvhd in a PD-1 Dependent Manner
 Deng,Ruishu;Cassady,Kaniel;Li,Xiaofan;
BLOOD 124 21 DEC 6 2014

44.Myeloid Cells' Evasion of Melanoma Immunity
 Wang,Jun;Chen,Lieping
JOURNAL OF INVESTIGATIVE DERMATOLOGY 134 11 2675-2677 NOV 2014
 1 
45.Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression
 Chen,Limo;Gibbons,Don L.;Goswami,Sangeeta;
NATURE COMMUNICATIONS 5 5241 OCT 2014
 187 
46.Association of PD-1,PD-1 Ligands,and Other Features of the Tumor Immune Microenvironment with Response to Anti-PD-1 Therapy
 Taube,Janis M.;Klein,Alison;Brahmer,Julie R.;
CLINICAL CANCER RESEARCH 20 19 5064-5074 OCT 1 2014
 904 
47.Programmed Death-1 Pathway in Host Tissues Ameliorates Th17/Th1-Mediated Experimental Chronic Graft-versus-Host Disease
 Fujiwara,Hideaki;Maeda,Yoshinobu;Kobayashi,Koichiro;
JOURNAL OF IMMUNOLOGY 193 5 2565-2573 SEP 1 2014
 30 
48.Inducible Expression of B7-H1 (PD-L1) and Its Selective Role in Tumor Site Immune Modulation
 Sanmamed,Miguel F.;Chen,Lieping
CANCER JOURNAL 20 4 256-261 JUL-AUG 2014
 49 
49.PD-1 as an Immune Modulatory Receptor
 Yao,Sheng;Chen,Lieping
CANCER JOURNAL 20 4 262-264 JUL-AUG 2014
 32 
50.From the Guest Editor Tumor Site Immune Modulation Therapy
 Chen,Lieping
CANCER JOURNAL 20 4 254-255 JUL-AUG 2014
 4 
51.Targeting CD137 enhances the efficacy of cetuximab
 Kohrt,Holbrook E.;Colevas,A. Dimitrios;Houot,Roch;
JOURNAL OF CLINICAL INVESTIGATION 124 6 2668-2682 JUN 2014
 91 
52.
Regulation of tumor cell PD-L1 expression by microRNA-200 and control of lung cancer metastasis
 Gibbons,Don Lynn;Chen,Limo;Goswami,Sangeeta;
JOURNAL OF CLINICAL ONCOLOGY 32 15 S 8063 MAY 20 2014
  1 
53.Coinhibitory receptor PD-1H preferentially suppresses CD4(+) T cell-mediated immunity
 Flies,Dallas B.;Han,Xue;Higuchi,Tomoe;
JOURNAL OF CLINICAL INVESTIGATION 124 5 1966-1975 MAY 2014
 50 
54.Anti-TOSO antibody treatment promotes T cell activation-induced cell death (AICD) in vitro and in vivo
 Tan,Yi;Han,Xue;Wu,Xiaoran;
CHINESE SCIENCE BULLETIN 59 13 1374-1385 MAY 2014

55.Excess LIGHT Contributes to Placental Impairment,Increased Secretion of Vasoactive Factors,Hypertension,and Proteinuria in Preeclampsia
 Wang,Wei;Parchim,Nicholas F.;Iriyama,Takayuki;
HYPERTENSION 63 3 595-606 MAR 2014
 18 
56.Hair Follicle Mesenchyme-Associated PD-L1 Regulates T-Cell Activation Induced Apoptosis A Potential Mechanism of Immune Privilege
 Wang,Xiaojie;Marr,Alexandra K.;Breitkopf,Trisia;
JOURNAL OF INVESTIGATIVE DERMATOLOGY 134 3 736-745 MAR 2014
 13 
57.Tissue-Expressed B7-H1 Critically Controls Intestinal Inflammation
 Scandiuzzi,Lisa;Ghosh,Kaya;Hofmeyer,Kimberly A.;
CELL REPORTS 6 4 625-632 FEB 2014
 17 
58.microRNA-200 regulates tumor cell PD-L1 expression to control lung cancer metastasis.
 Gibbons,Don L.;Chen,Limo;Goswami,Sangeeta;
CLINICAL CANCER RESEARCH 20 2 A21 JAN 15 2014

59.CD137 as a Biomarker for Tumor-Reactive T Cells Finding Gold in the Desert
 Zhu,Yuwen;Chen,Lieping
CLINICAL CANCER RESEARCH 20 1 3-5 JAN 1 2014
 5 
60.The growth of private hospitals and their health workforce in China a comparison with public hospitals
 Tang,Chengxiang;Zhang,Yucheng;Chen,Lieping;
HEALTH POLICY AND PLANNING 29 1 30-41 JAN 2014
 8 
61.Programmed death ligand-1 expression in non-small cell lung cancer
 Velcheti,Vamsidhar;Schalper,Kurt A.;Carvajal,Daniel E.;
LABORATORY INVESTIGATION 94 1 107-116 JAN 2014
 398 
62.Host Tissue PD-1 Pathway Contribute To Murine Chronic Graft-Versus-Host Disease Via Th1+Th17+Cells
 Fujiwara,Hideaki;Maeda,Yoshinobu;Kobayashi,Koichiro;
BLOOD 122 21 3244 NOV 15 2013

63.Antagonist Antibodies to PD-1 and B7-H1 (PD-L1) in the Treatment of Advanced Human Cancer-Response
 Sznol,Mario;Chen,Lieping
CLINICAL CANCER RESEARCH 19 19 5542-5542 OCT 1 2013
 47 
64.CD137 Facilitates the Resolution of Acute DSS-Induced Colonic Inflammation in Mice
 Gomez,Julia M. Martinez;Chen,Lieping;Schwarz,Herbert;
PLOS ONE 8 9 e73277 SEP 4 2013
 7 
65.B7-H4Ig inhibits mouse and human T-cell function and treats EAE via IL-10/Treg-dependent mechanisms
 Podojil,Joseph R.;Liu,Linda N.;Marshall,Shannon A.;
JOURNAL OF AUTOIMMUNITY 44 71-81 AUG 2013
 27 
66.Molecular mechanisms of T cell co-stimulation and co-inhibition (vol 13,pg 27,2013)
 Chen,Lieping;Flies,Dallas B.
NATURE REVIEWS IMMUNOLOGY 13 7 JUL 2013

67.Remission of Recent Onset Type 1 Diabetes in NOD Mice by Treatment of Fusion Protein B7-H4-Immunoglobulin
 Lee,I-Fang;Wang,Xiaojie;Hao,Jianqiang;
DIABETES 62 1 A442-A442 1694-P JUL 2013

68.Toxoplasma gondii Rhoptry 16 Kinase Promotes Host Resistance to Oral Infection and Intestinal Inflammation Only in the Context of the Dense Granule Protein GRA15
 Jensen,Kirk D. C.;Hu,Kenneth;Whitmarsh,Ryan J.;
INFECTION AND IMMUNITY 81 6 2156-2167 JUN 2013
 34 
69.B7-H5 costimulates human T cells via CD28H
 Zhu,Yuwen;Yao,Sheng;Iliopoulou,Bettina P.;
NATURE COMMUNICATIONS 4 2043 JUN 2013
 36 
70.CD137 ligand signaling enhances myelopoiesis during infections
 Tang,Qianqiao;Jiang,Dongsheng;Alonso,Sylvie;
EUROPEAN JOURNAL OF IMMUNOLOGY 43 6 1555-1567 JUN 2013
 10 
71.Clinical and pharmacodynamic (PD) results of a phase I trial with AMP-224 (B7-DC Fc) that binds to the PD-1 receptor.
 Infante,Jeffrey R.;Powderly,John D.;Burris,Howard A.;
JOURNAL OF CLINICAL ONCOLOGY 31 15 S 3044 MAY 20 2013 

72.Targeting CD137 to enhance the antitumor efficacy of cetuximab by stimulation of innate and adaptive immunity.
 Kohrt,Holbrook Edwin;Houot,Roch;Weiskopf,Kipp;
JOURNAL OF CLINICAL ONCOLOGY 31 15 S 3015 MAY 20 2013
 1 
73.Clinical significance of programmed death ligand-1 expression in non-small cell lung cancer (NSCLC)
 Velcheti,Vamsidhar;Schalper,Kurt;Carvajal,Daniel;
JOURNAL OF CLINICAL ONCOLOGY 31 15 S 11075 MAY 20 2013

74.Lymphatic endothelial cells induce anergy of beta-galactosidase specific CD4 T cells by providing antigen to CD11c cells
 Rouhani,Sherin;Tewalt,Eric;Davis,Holly;
JOURNAL OF IMMUNOLOGY 190 P1147 MAY 1 2013

75.Phase I study of safety,tolerability,pharmacokinetics,and pharmacodynamics of AMP-224 (B7-DC Fc fusion protein) in a regimen containing cyclophosphamide (CTX) in patients with advanced solid tumors.
 LoRusso,Patricia M.;Powderly,John;Burris,Howard A.;
 CANCER RESEARCH 73 8 1 LB193 APR 15 2013
 2 
76.Molecular mechanisms of T cell co-stimulation and co-inhibition
 Chen,Lieping;Flies,Dallas B.
NATURE REVIEWS IMMUNOLOGY 13 4 227-242 APR 2013
 752 
77.Evidence for a Role of the PD-1PD-L1 Pathway in Immune Resistance of HPV-Associated Head and Neck Squamous Cell Carcinoma
 Lyford-Pike,Sofia;Peng,Shiwen;Young,Geoffrey D.;
CANCER RESEARCH 73 6 1733-1741 MAR 15 2013
 308 
78.B7-H4.Ig inhibits the development of Type 1 diabetes by regulating Th17 cells in NOD mice
 Lee,I-Fang;Wang,Xiaojie;Hao,Jianqiang;
CELLULAR IMMUNOLOGY 282 1 1-8 MAR 2013
 14 
79.Antagonist Antibodies to PD-1 and B7-H1 (PD-L1) in the Treatment of Advanced Human Cancer
 Sznol,Mario;Chen,Lieping
CLINICAL CANCER RESEARCH 19 5 1021-1034 MAR 1 2013
 274 
80.Adaptive resistance A tumor strategy to evade immune attack
 Yao,Sheng;Chen,Lieping
EUROPEAN JOURNAL OF IMMUNOLOGY 43 3 576-579 MAR 2013
 9 
81.Advances in targeting cell surface signalling molecules for immune modulation
 Yao,Sheng;Zhu,Yuwen;Chen,Lieping
NATURE REVIEWS DRUG DISCOVERY 12 2 130-146 FEB 2013
 133 
82.Durable Cancer Regression Off-Treatment and Effective Reinduction Therapy with an Anti-PD-1 Antibody
 Lipson,Evan J.;Sharfman,William H.;Drake,Charles G.;
CLINICAL CANCER RESEARCH 19 2 462-468 JAN 15 2013
 284 
83.Endogenous Expression of B7-H4 Improves Long-term Murine Islet Allograft Survival
 Wang,Xiaojie;Hao,Jianqiang;Metzger,Daniel L.;
TRANSPLANTATION 95 1 94-99 JAN 15 2013
 9 
84.Immunohistochemical Staining of B7-H1 (PD-L1) on Paraffin-embedded Slides of Pancreatic Adenocarcinoma Tissue
 Bigelow,Elaine;Bever,Katherine M.;Xu,Haiying;
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS 71 UNSP e4059 JAN 2013
 29 
85.Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells
 Tewalt,Eric F.;Cohen,Jarish N.;Rouhani,Sherin J.;
BLOOD 120 24 4772-4782 DEC 6 2012
 82 
86.Safety,Activity,and Immune Correlates of Anti-PD-1 Antibody in Cancer
 Topalian,Suzanne L.;Hodi,F. Stephen;Brahmer,Julie R.;
NEW ENGLAND JOURNAL OF MEDICINE 366 26 2443-2454 JUN 28 2012
 5,149 
87.PD-1 Blockage Reverses Immune Dysfunction and Hepatitis B Viral Persistence in a Mouse Animal Model
 Tzeng,Horng-Tay;Tsai,Hwei-Fang;Liao,Hsiu-Jung;
PLOS ONE 7 6 e39179 JUN 22 2012
 80 
88.Cancer-Induced Immunosuppression IL-18-Elicited Immunoablative NK Cells
 Terme,Magali;Ullrich,Evelyn;Aymeric,Laetitia;
CANCER RESEARCH 72 11 2757-2767 JUN 1 2012
 62 
89.The B7 Homologues and their Receptors in Hematologic Malignancies
 Wilcox,Ryan A.;Ansell,Stephen M.;Lim,Megan S.;
EUROPEAN JOURNAL OF HAEMATOLOGY 88 6 465-475 JUN 2012
 15 
90.Increased NKT Cells in B7-H4.Ig-Mediated Protection of Type 1 Diabetes
 Lee,I-Fang;Wang,Xiaojie;Hao,Jianqiang;
DIABETES 61 1 A406-A406 1563-P JUN 1 2012

91.Effect of stimulation of natural killer cells with an anti-CD137 mAb on the efficacy of trastuzumab,cetuximab,and rituximab
 Kohrt,Holbrook Edwin;Houot,Roch;Weiskopf,Kipp;
JOURNAL OF CLINICAL ONCOLOGY 30 15 S 2514 MAY 20 2012

92.PD-1PD-L1(B7-H1) pathway in adaptive resistance A novel mechanism for tumor immune escape in human papillomavirus-related head and neck cancers.
 Lyford-Pike,Sofia;Peng,Shiwen;Taube,Janis M.;
JOURNAL OF CLINICAL ONCOLOGY 30 15 S 5506 MAY 20 2012

93.Peripheral tolerance induction by PD-L1+lymphatic endothelial cell is due to deficient costimulation that leads to rapid,high-level expression of PD-1 on CD8 T cells
 Tewalt,Eric;Cohen,Jarish;Rouhani,Sherin;
JOURNAL OF IMMUNOLOGY 188 MAY 1 2012 

94.Peripheral tolerance induction by PD-L1+lymphatic endothelial cell is due to deficient costimulation that leads to rapid,high-level expression of PD-1 on CD8 T cells
 Tewalt,Eric;Cohen,Jarish;Rouhani,Sherin;
JOURNAL OF IMMUNOLOGY 188 MAY 1 2012

95.The B7-CD28 paradigm revisited- a systemic receptor array approach
 Yao,Sheng;Zhu,Yuwen;Zhu,Gefeng;
JOURNAL OF IMMUNOLOGY 188 MAY 1 2012

96.Stimulation of natural killer cells with an anti-CD137 antibody enhances the efficacy trastuzumab,cetuximab,and rituximab in HER2-expressing breast cancer,EGFR plus head and neck cancer,and CD20+lymphoma
 Kohrt,Holbrook;Houot,Roch;Weiskopf,Kipp;
CANCER RESEARCH 72 8 LB-138 APR 15 2012

97.Colocalization of Inflammatory Response with B7-H1 Expression in Human Melanocytic Lesions Supports an Adaptive Resistance Mechanism of Immune Escape
 Taube,Janis M.;Anders,Robert A.;Young,Geoffrey D.;
SCIENCE TRANSLATIONAL MEDICINE 4 127 127ra37 MAR 28 2012
 771 
98.Stimulation of natural killer cells with a CD137-specific antibody enhances trastuzumab efficacy in xenotransplant models of breast cancer
 Kohrt,Holbrook E.;Houot,Roch;Weiskopf,Kipp;
JOURNAL OF CLINICAL INVESTIGATION 122 3 1066-1075 MAR 2012
 131 
99.Expression of anti-HVEM single-chain antibody on tumor cells induces tumor-specific immunity with long-term memory
 Park,Jang-June;Anand,Sudarshan;Zhao,Yuming;
CANCER IMMUNOLOGY IMMUNOTHERAPY 61 2 203-214 FEB 2012
 4 
100.Loss of B7-H1 Expression by Recipient Parenchymal Cells Leads to Expansion of Infiltrating Donor CD8(+) T Cells and Persistence of Graft-Versus-Host Disease
 Li,Xiaofan;Deng,Ruishu;He,Wei;
JOURNAL OF IMMUNOLOGY 188 2 724-734 JAN 15 2012
 14 
101.B7-H4 Treatment of T Cells Inhibits ERK,JNK,p38,and AKT Activation
 Wang,Xiaojie;Hao,Jianqiang;Metzger,Daniel L.;
PLOS ONE 7 1 e28232 JAN 4 2012
 59 
102.B7-H4 Induces Donor-Specific Tolerance in Mouse Islet Allografts
 Wang,Xiaojie;Hao,Jianqiang;Metzger,Daniel L.;
CELL TRANSPLANTATION 21 1 99-111 2012
 9 
103.Early Treatment of NOD Mice With B7-H4 Reduces the Incidence of Autoimmune Diabetes
 Wang,Xiaojie;Hao,Jianqiang;Metzger,Daniel L.;
DIABETES 60 12 3246-3255 DEC 2011
 27 
104.Herpesvirus entry mediator regulates hypoxia-inducible factor-1 alpha and erythropoiesis in mice
 Sakoda,Yukimi;Anand,Sudarshan;Zhao,Yuming;
JOURNAL OF CLINICAL INVESTIGATION 121 12 4810-4819 DEC 2011
 9 
105.B7-H1 Molecules on Myeloma Cells Induce Aggressive Cell Behavior
 Tamura,Hideto;Ishibashi,Mariko;Yamashita,Taishi;
BLOOD 118 21 219-220 NOV 18 2011

106.Tissue Parenchymal Cell Expression of B7-H1 Inhibits Infiltrating T Cell Expansion and Prevents Persistence of Graft-Versus-Host Disease
 Li,Xiaofan;He,Wei;Deng,Ruishu;
BLOOD 118 21 1282-1283 NOV 18 2011

107.BLOCKADE OF BOTH B7-H4 AND CTLA-4 CO-SIGNALING PATHWAYS ENHANCES MOUSE ISLET ALLOGRAFT SURVIVAL
 Wang,Xiaojie;Hao,Jianqiang;Mertzger,Daniel;
TRANSPLANT INTERNATIONAL 24 特刊 SI 2 178-178 SEP 2011

108.Cutting Edge A Monoclonal Antibody Specific for the Programmed Death-1 Homolog Prevents Graft-versus-Host Disease in Mouse Models
 Flies,Dallas B.;Wang,Shengdian;Xu,Haiying;
JOURNAL OF IMMUNOLOGY 187 4 1537-1541 AUG 15 2011
 67 
109.Ex Vivo Expanded Hematopoietic Stem Cells Overcome the MHC Barrier in Allogeneic Transplantation
 Zheng,Junke;Umikawa,Masato;Zhang,Shichuan;
CELL STEM CELL 9 2 119-130 AUG 5 2011
 39 
110.The development and functions of CD4(+) T cells expressing a transgenic TCR specific for an MHC-I-restricted tumor antigenic epitope
 Han,Xue;Ye,Peiying;Luo,Liqun;
CELLULAR & MOLECULAR IMMUNOLOGY 8 4 333-340 JUL 2011
 1 
111.B7-H2 Is a Costimulatory Ligand for CD28 in Human
 Yao,Sheng;Zhu,Yuwen;Zhu,Gefeng;
IMMUNITY 34 5 729-740 MAY 27 2011
 72 
112.Blockade of B7-H1 (Programmed Death Ligand 1) Enhances Humoral Immunity by Positively Regulating the Generation of T Follicular Helper Cells
 Hams,Emily;McCarron,Mark J.;Amu,Sylvie;
JOURNAL OF IMMUNOLOGY 186 10 5648-5655 MAY 15 2011
 82 
113.Lymphotoxin Signal Promotes Thymic Organogenesis by Eliciting RANK Expression in the Embryonic Thymic Stroma
 Mouri,Yasuhiro;Yano,Masashi;Shinzawa,Miho;
JOURNAL OF IMMUNOLOGY 186 9 5047-5057 MAY 1 2011
 49 
114.Cell Surface Signaling Molecules in the Control of Immune Responses A Tide Model
 Zhu,Yuwen;Yao,Sheng;Chen,Lieping
IMMUNITY 34 4 466-478 APR 22 2011
 65 
115.Host APCs Augment In Vivo Expansion of Donor Natural Regulatory T Cells via B7H1/B7.1 in Allogeneic Recipients
 Yi,Tangsheng;Li,Xiaofan;Yao,Sheng;
JOURNAL OF IMMUNOLOGY 186 5 2739-2749 MAR 1 2011
 29 
116.CD137 stimulation enhances the antilymphoma activity of anti-CD20 antibodies
 Kohrt,Holbrook E.;Houot,Roch;Goldstein,Matthew J.;
BLOOD 117 8 2423-2432 FEB 24 2011
 138 
117.
Immunobiology of Cancer Therapies Targeting CD137 and B7-H1/PD-1 Cosignal Pathways
 Wang,Shengdian;Chen,Lieping
CANCER IMMUNOLOGY AND IMMUNOTHERAPY 丛书 Current Topics in Microbiology and Immunology 344 245-267 2011
 23 
118.CD137-Mediated Pathogenesis from Chronic Hepatitis to Hepatocellular Carcinoma in Hepatitis B Virus-Transgenic Mice
 Wang,Jun;Zhao,Wenxia;Cheng,Liang;
JOURNAL OF IMMUNOLOGY 185 12 7654-7662 DEC 15 2010
 26 
119.Immunomodulation of NK Cells through 4-1BB (CD137) to Improve the Anti-Lymphoma Activity of Rituximab Antibody-Based Anti-Lymphoma
 Kohrt,Holbrook E.;Houot,Roch;Goldstein,Matthew J.;
BLOOD 116 21 188-189 NOV 19 2010
 1 
120.Immunotherapeutic Potential of B7-DC (PD-L2) Cross-Linking Antibody In Conferring Antitumor Immunity (Retraction of vol 64,pg 4965,2004)
 Nguyen,Loc T.;Ciric,Bogoljub;Van Keulen,Virginia P.;
CANCER RESEARCH 70 22 9528-9528 NOV 15 2010

121.B7-H1 expression on non-B and non-T cells promotes distinct effects on T- and B-cell responses in autoimmune arthritis
 Hamel,Keith M.;Cao,Yanxia;Wang,Yumei;
EUROPEAN JOURNAL OF IMMUNOLOGY 40 11 3117-3127 NOV 2010
 45 
122.Crucial roles of B7-H1 and B7-DC expressed on mesenteric lymph node dendritic cells in the generation of antigen-specific CD4(+)Foxp3(+) regulatory T cells in the establishment of oral tolerance
 Fukaya,Tomohiro;Takagi,Hideaki;Sato,Yumiko;
BLOOD 116 13 2266-2276 SEP 30 2010
 47 
123.B7-H1-Dependent Sex-Related Differences in Tumor Immunity and Immunotherapy Responses
 Lin,Pei-Yi;Sun,Lishi;Thibodeaux,Suzanne R.;
JOURNAL OF IMMUNOLOGY 185 5 2747-2753 SEP 1 2010
 49 
124.B7-H1/CD80 interaction is required for the induction and maintenance of peripheral T-cell tolerance
 Park,Jang-June;Omiya,Ryusuke;Matsumura,Yumiko;
BLOOD 116 8 1291-1298 AUG 26 2010
 163 
125.Interferon-gamma and tumor necrosis factor-alpha induce an immunoinhibitory molecule,B7-H1,via nuclear factor-kappa B activation in blasts in myelodysplastic syndromes
 Kondo,Asaka;Yamashita,Taishi;Tamura,Hideto;
BLOOD 116 7 1124-1131 AUG 19 2010
 93 
126.Treatment with anti-CD137 mAbs causes intense accumulations of liver T cells without selective antitumor immunotherapeutic effects in this organ
 Dubrot,Juan;Milheiro,Francisca;Alfaro,Carlos;
CANCER IMMUNOLOGY IMMUNOTHERAPY 59 8 1223-1233 AUG 2010
 51 
127.Deficiency in B7-H1 (PD-L1)/PD-1 Coinhibition Triggers Pancreatic beta-Cell Destruction by Insulin-Specific,Murine CD8 T-Cells
 Rajasalu,Tarvo;Brosi,Helen;Schuster,Cornelia;
DIABETES 59 8 1966-1973 AUG 2010
 25 
128.Phase I Study of Single-Agent Anti-Programmed Death-1 (MDX-1106) in Refractory Solid Tumors Safety,Clinical Activity,Pharmacodynamics,and Immunologic Correlates
 Brahmer,Julie R.;Drake,Charles G.;Wollner,Ira;
JOURNAL OF CLINICAL ONCOLOGY 28 19 3167-3175 JUL 1 2010
 1,367 
129.Improving Islet Allograft Survival by Activating Two Negative Co-Signaling Pathways
 Wang,Xiaojie;Hao,Jiangiang;Metzger,Daniel L.;
 DIABETES 59 1 A44-A44 JUN 2010

130.Naturally Occurring Human IgM Antibody That Binds B7-DC and Potentiates T Cell Stimulation by Dendritic Cells (Retraction of vol 170,pg 1830,2003)
 Radhakrishnan,Suresh;Nguyen,Loc T.;Ciric,Bogoljub;
JOURNAL OF IMMUNOLOGY 184 11 6552-6552 JUN 1 2010
 1 
131.PD-1 regulates germinal center B cell survival and the formation and affinity of long-lived plasma cells
 Good-Jacobson,Kim L.;Szumilas,Courtney G.;Chen,Lieping;
NATURE IMMUNOLOGY 11 6 535-U107 JUN 2010
 320 
132.Cross-linking the B7 family molecule B7-DC directly activates immune functions of dendritic cells (Retraction of vol 196,pg 1393,2002)
 Nguyen,Loc T.;Radhakrishnan,Suresh;Ciric,Bogoljub;
JOURNAL OF EXPERIMENTAL MEDICINE 207 4 APR 12 2010

133.CD137 agonist antibody prevents cancer recurrence contribution of CD137 on both hematopoietic and nonhematopoietic cells
 Narazaki,Hidehiko;Zhu,Yuwen;Luo,Liqun;
BLOOD 115 10 1941-1948 MAR 11 2010
 29 
134.Costimulator B7-DC Attenuates Strong Th2 Responses Induced by Nippostrongylus brasiliensis
 Ishiwata,Kenji;Watanabe,Naohiro;Guo,Miao;
JOURNAL OF IMMUNOLOGY 184 4 2086-2094 FEB 15 2010
 26 
135.Structural immunology of costimualtory and coinhibitory molecules
 Wang ShengDian;Chen LiePing
SCIENCE CHINA-LIFE SCIENCES 53 2 183-189 FEB 2010
 9 
136.Leucocyte-associated immunoglobulin-like receptor-1 is an inhibitory regulator of contact hypersensitivity
 Omiya,Ryusuke;Tsushima,Fumihiko;Narazaki,Hidehiko;
IMMUNOLOGY 128 4 543-555 DEC 2009
 10 
137.NOD2 Ligation Subverts IFN-alpha Production by Liver Plasmacytoid Dendritic Cells and Inhibits Their T Cell Allostimulatory Activity via B7-H1 Up-Regulation
 Castellaneta,Antonino;Sumpter,Tina L.;Chen,Lieping;
JOURNAL OF IMMUNOLOGY 183 11 6922-6932 DEC 1 2009
 46 
138.Therapeutic Potential of Anti-CD137 Antibody in Lymphoma
 Houot,Roch;Goldstein,Matthew J.;Kohrt,Holbrook E.;
BLOOD 114 22 301-302 NOV 20 2009

139.Interferon-gamma and Tumor Necrosis Factor-alpha Induce An Immumoinhibitory Molecule,B7-H1,Via Nf kappa B Activation in Blasts of Myelodysplastic Syndromes.
 Kondo,Asaka;Tamura,Hideto;Yamashita,Taishi;
BLOOD 114 22 1081-1082 NOV 20 2009

140.Therapeutic effect of CD137 immunomodulation in lymphoma and its enhancement by T-reg depletion
 Houot,Roch;Goldstein,Matthew J.;Kohrt,Holbrook E.;
BLOOD 114 16 3431-3438 OCT 15 2009
 60 
141.Kupffer Cell Suppression of CD8(+) T Cells in Human Hepatocellular Carcinoma Is Mediated by B7-H1/Programmed Death-1 Interactions
 Wu,Ke;Kryczek,Ilona;Chen,Lieping;
CANCER RESEARCH 69 20 8067-8075 OCT 15 2009
 155 
142.Tumor-Expressed B7-H1 and B7-DC in Relation to PD-1+T-Cell Infiltration and Survival of Patients with Cervical Carcinoma
 Karim,Rezaul;Jordanova,Ekaterina S.;Piersma,Sytse J.;
CLINICAL CANCER RESEARCH 15 20 6341-6347 OCT 15 2009
 142 
143.Potential Role of Decoy B7-H4 in the Pathogenesis of Rheumatoid Arthritis A Mouse Model Informed by Clinical Data
 Azuma,Takeshi;Zhu,Gefeng;Xu,Haiying;
PLOS MEDICINE 6 10 e1000166 OCT 2009
 44 

144.Reciprocal differentiation and tissue-specific pathogenesis of Th1,Th2,and Th17 cells in graft-versus-host disease
 Yi,Tangsheng;Chen,Ying;Wang,Lin;
BLOOD 114 14 3101-3112 OCT 1 2009
 179 
145.B and T Lymphocyte Attenuator Tempers Early Infection Immunity
 Sun,Yonglian;Brown,Nicholas K.;Ruddy,Matthew J.;
JOURNAL OF IMMUNOLOGY 183 3 1946-1951 AUG 1 2009
 37 
146.PD-1 on dendritic cells impedes innate immunity against bacterial infection
 Yao,Sheng;Wang,Shengdian;Zhu,Yuwen;
BLOOD 113 23 5811-5818 JUN 4 2009
 97 
147.B7-H4 Is a Candidate Biomarker for Type 1 Diabetes in Pancreatic Islets
 Cheung,Susan S. C.;Ou,Dawei;Metzger,Daniel L.;
DIABETES 58 A324-A324 JUN 2009

148.Fine tuning the immune response through B7-H3 and B7-H4
 Yi,Kyung H.;Chen,Lieping
IMMUNOLOGICAL REVIEWS 229 145-151 MAY 2009
 112 
149.Target-Dependent B7-H1 Regulation Contributes to Clearance of Central Nervous Sysyem Infection and Dampens Morbidity
 Phares,Timothy W.;Ramakrishna,Chandran;Parra,Gabriel I.;
JOURNAL OF IMMUNOLOGY 182 9 5430-5438 MAY 1 2009
 38 

150.Non-lymphoid expression of B7-H1 regulates severity of proteoglycan-induced arthritis
 Homel,Keith M.;Doodes,Paul;Cao,Yanxia;
JOURNAL OF IMMUNOLOGY 182 1 137.24 APR 1 2009

 151.Reciprocal differentiation and tissue-specific pathogenesis of Th1,Th2,and Th17 cells in graft versus host disease
 Yi,Tongsheng;Chen,Ying;Wang,Lin;
JOURNAL OF IMMUNOLOGY 182 1 141.13 APR 1 2009

152.Palettes of Vaccines and Immunostimulatory Monoclonal Antibodies for Combination
 Melero,Ignacio;Martinez-Forero,Ivan;Dubrot,Juan;
CLINICAL CANCER RESEARCH 15 5 1507-1509 MAR 1 2009
 19 
153.Turning the Tide of Lymphocyte Costimulation
 Zhu,Yuwen;Chen,Lieping
JOURNAL OF IMMUNOLOGY 182 5 2557-2558 MAR 1 2009
 2 
154.Local Expression of B7-H4 by Recombinant Adenovirus Transduction in Mouse Islets Prolongs Allograft Survival
 Wang,Xiaojie;Hao,Jianqiang;Metzger,Daniel L.;
TRANSPLANTATION 87 4 482-490 FEB 27 2009
 29 
155.B7-H1 (PD-L1) on T cells is required for T-cell-mediated conditioning of dendritic cell maturation
 Talay,Oezcan;Shen,Ching-Hung;Chen,Lieping;
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 106 8 2741-2746 FEB 24 2009
 38 
156.B7-H4-deficient mice display augmented neutrophil-mediated innate immunity
 Zhu,Gefeng;Augustine,Mathew M.;Azuma,Takeshi;
BLOOD 113 8 1759-1767 FEB 19 2009
 58 
157.Functional B7.2 and B7-H2 Molecules on Myeloma Cells Are Associated with a Growth Advantage
 Yamashita,Thishi;Tamura,Hideto;Satoh,Chikako;
CLINICAL CANCER RESEARCH 15 3 770-777 FEB 1 2009
 23 
158.Radiation-Free Anti-CD3-Conditioning Regimen Maintains Tissue Protection Mechanisms and Prevents GVHD Role of Tissue Expression of B7H1
 Chen,Ying;Lin,Chia-Lei;Li,Nainong;
BLOOD 112 11 30-30 NOV 16 2008

159.Expression and Function of B7.2 and B7-H2 Molecules on Myeloma Cells.
 Yamashita,Taishi;Tamura,Hideto;Sato,Chikako;
BLOOD 112 11 940-941 NOV 16 2008

160.Cutting Edge IFN-gamma Enables APC to Promote Memory Th17 and Abate Th1 Cell Development
 Kryczek,Ilona;Wei,Shuang;Gong,Wenrong;
JOURNAL OF IMMUNOLOGY 181 9 5842-5846 NOV 1 2008
 47 
161.Neurological and behavioral abnormalities,ventricular dilatation,altered cellular functions,inflammation,and neuronal injury in brains of mice due to common,persistent,parasitic infection
 Hermes,Gretchen;Ajioka,James W.;Kelly,Krystyna A.;
JOURNAL OF NEUROINFLAMMATION 5 48 OCT 23 2008
 90 
162.PD-1 ligands expressed on myeloid-derived APC in the CNS regulate T-cell responses in EAE
 Schreiner,Bettina;Bailey,Samantha L.;Shin,Tahiro;
EUROPEAN JOURNAL OF IMMUNOLOGY 38 10 2706-2717 OCT 2008
 63 
163.Non-lymphoid expression of B7-H1 regulates severity of proteoglycan-induced arthritis
 Hamel,Keit H. M.;Doodes,Paul D.;Cao,Yanxia;
ARTHRITIS AND RHEUMATISM 58 9 S S453-S453 SEP 2008

164.B7-H1 on hepatocytes facilitates priming of specific CD8 T cells but limits the specific recall of primed responses
 Wahl,Christian;Bochtler,Petra;Chen,Lieping;
GASTROENTEROLOGY 135 3 980-988 SEP 2008
 25 
165.Fc-dependent expression of CD137 on human NK cells insights into "agonistic" effects of anti-CD137 monoclonal antibodies
 Lin,Wei;Voskens,Caroline J.;Zhang,Xiaoyu;
BLOOD 112 3 699-707 AUG 1 2008
 61 
166.Tumor-induced immune suppression of in vivo effector T-cell priming is mediated by the B7-H1/PD-1 axis and transforming growth factor beta
 Wei,Shuang;Shreiner,Andrew B.;Takeshita,Nobuhiro;
CANCER RESEARCH 68 13 5432-5438 JUL 1 2008
 56 
167.Improving allograft survival in islet transplantation by local B7-H4 over-expression
 Wang,Xiaojie;Hao,Jianqiang;Metzger,Daniel L.;
DIABETES 57 1 A78-A78 JUN 2008
 1 
168.B7-H1 restricts neuroantigen-specific T cell responses and confines inflammatory CNS damage Implications for the lesion pathogenesis of multiple sclerosis
 Ortler,Sonja;Leder,Christoph;Mittelbronn,Michel;
EUROPEAN JOURNAL OF IMMUNOLOGY 38 6 1734-1744 JUN 2008
 40 
169.Detrimental contribution of the immuno-inhibitor B7-H1 to rabies virus encephalitis
 Lafon,Monique;Megret,Francoise;Meuth,Sven G.;
JOURNAL OF IMMUNOLOGY 180 11 7506-7515 JUN 1 2008
 63 
170.Inhibitory B7-family molecules in the tumour microenvironment
 Zou,Weiping;Chen,Lieping
NATURE REVIEWS IMMUNOLOGY 8 6 467-477 JUN 2008
 768 
171.B7-H1 is a ubiquitous antiapoptotic receptor on cancer cells
 Azuma,Takeshi;Yao,Sheng;Zhu,Gefeng;
BLOOD 111 7 3635-3643 APR 1 2008
 215 
172.CD137 is expressed in human atherosclerosis and promotes development of plaque inflammation in hypercholesterolemic mice
 Olofsson,Peder S.;Soderstrom,Leif A.;Wagsater,Dick;
CIRCULATION 117 10 1292-1301 MAR 11 2008
 151 
173.Blocking of monocyte-associated B7-H1 (CD274) enhances HCV-specific T cell immunity in chronic hepatitis C infection
 Jeong,Hye-Young;Lee,Youn-Jae;Seo,Su-Kil;
JOURNAL OF LEUKOCYTE BIOLOGY 83 3 755-764 MAR 1 2008

 36 
174.Tolerogenic maturation of liver sinusoidal endothelial cells promotes B7-homolog 1-dependent CD8(+) T cell tolerance
 Diehl,Linda;Schurich,Anna;Grochtmann,Regina;
HEPATOLOGY 47 1 296-305 JAN 2008

 136 
175.Blockade of endogenous B7-H1 suppresses antibacterial protection after primary Listeria monocytogenes infection
 Seo,Su-Kil;Jeong,Hye-Young;Park,Sae-Gwang;
IMMUNOLOGY 123 1 90-99 JAN 2008
 24 
176.Multivalent 4-1BB binding aptamers costimulate CD8(+) T cells and inhibit tumor growth in mice
 McNamara,James O.,II;Kolonias,Despina;Pastor,Fernando;
JOURNAL OF CLINICAL INVESTIGATION 118 1 376-386 JAN 2008
 173 
177.Programmed death-1 concentration at the immunologicial synapse is determined by ligand affinity and availability
 Pentcheva-Hoang,Tsvetelina;Chen,Lieping;Pardoll,Drew M.;
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 104 45 17765-17770 NOV 6 2007
 50 
178.Relationship between B7-H4,regulatory T cells,and patient outcome in human ovarian carcinoma
 Kryczek,Ilona;Wei,Shuang;Zhu,Gefeng;
CANCER RESEARCH 67 18 8900-8905 SEP 15 2007
 207 
179.Interaction between B7-H1 and PD-1 determines initiation and reversal of T-cell anergy
 Tsushima,Fumihiko;Yao,Sheng;Shin,Tahiro;
BLOOD 110 1 180-185 JUL 1 2007
 126 
180.Role of PD-1 and its ligand,B7-H1,in early fate decisions of CD8 T cells
 Goldberg,Monica V.;Maris,Charles H.;Hipkiss,Edward L.;
BLOOD 110 1 186-192 JUL 1 2007
 110 
181.How Ebola and Marburg viruses battle the immune system
 Mohamadzadeh,Mansour;Chen,Lieping;Schmaljohn,Alan L.
NATURE REVIEWS IMMUNOLOGY 7 7 556-567 JUL 2007
 
 84 
182.CD137 stimulation delivers an antigen-independent growth signal for T lymphocytes with memory phenotype
 Zhu,Yuwen;Zhu,Gefeng;Luo,Liqun;
BLOOD 109 11 4882-4889 JUN 1 2007
 61 
183.B7-H1 up-regulation on myeloid dendritic cells significantly suppresses T cell immune function in patients with chronic hepatitis B
 Chen,Liangen;Zhang,Zheng;Chen,Weiwei;
JOURNAL OF IMMUNOLOGY 178 10 6634-6641 MAY 15 2007
 118 
184.Requirement of the B7 homolog,B7-H4,in donor and recipient for induction of allograft tolerance.
 Wang,Liqing;Han,Rongxiang;Chen,Lieping;
AMERICAN JOURNAL OF TRANSPLANTATION 7 2 228-228 313 MAY 2007

185.Selective targeting of the LIGHT-HVEM costimulatory system for the treatment of graft-versus-host disease
 Xu,Yanhui;Flies,Andrew S.;Flies,Dallas B.;
BLOOD 109 9 4097-4104 MAY 1 2007
 47 
186.Cytokine-mediated disruption of lymphocyte trafficking,hemopoiesis,and induction of lymphopenia,anemia,and thrombocytopenia in anti-CD137-treated mice
 Niu,Liguo;Strahotin,Simona;Hewes,Becker;
JOURNAL OF IMMUNOLOGY 178 7 4194-4213 APR 1 2007
 101 
187.The new B7s Playing a pivotal role in tumor immunity
 Flies,Dallas B.;Chen,Lieping
JOURNAL OF IMMUNOTHERAPY 30 3 251-260 APR 2007

 123 
188.Effects of specific immunotherapy on the B7 family of costimulatory molecules in allergic inflammation
 Piconi,Stefania;Trabattoni,Daria;Saresella,Marina;
JOURNAL OF IMMUNOLOGY 178 3 1931-1937 FEB 1 2007
 13 
189.Immunostimulatory monoclonal antibodies for cancer therapy
 Melero,Ignacio;Hervas-Stubbs,Sandra;Glennie,Martin;
NATURE REVIEWS CANCER 7 2 95-106 FEB 2007

 390 
190.LIGHT-related molecular network in the regulation of innate and adaptive immunity
 Xu,Yanhui;Tamada,Koji;Chen,Lieping
IMMUNOLOGIC RESEARCH 37 1 17-31 2007

 3 
191.Filoviruses and the balance of innate,adaptive,and inflammatory responses
 Mohamadzadeh,Mansour;Chen,Lieping;Olinger,Gene G.;
VIRAL IMMUNOLOGY 19 4 602-612 WIN 2006

 20 
192.Mechanisms of GVL against a murine blast crisis CML.
 Shlomchik,Warren D.;Matte-Martone,Catherine C.;Gilliland,D. Gary;
BLOOD 108 11 60A-61A 子辑 1 191 NOV 16 2006
 2 
193.Human bone marrow A reservoir for "enhanced effector memory" CD8(+) T cells with potent recall function
 Zhang,Xiaoyu;Dong,Haidong;Lin,Wei;
JOURNAL OF IMMUNOLOGY 177 10 6730-6737 NOV 15 2006
 33 
194.Lymphocyte co-signal molecules in cancer immunotherapy
 Chen,Lieping
JOURNAL OF IMMUNOTHERAPY 29 6 664-664 NOV-DEC 2006
 2 
195.Modulation of immune response by B7 family molecules in tumor microenvironments
 Flies,Dallas B.;Chen,Lieping
IMMUNOLOGICAL INVESTIGATIONS 35 3-4 395-418 AUG-DEC 2006

 13 
196.Inhibition of Th2-mediated allergic airway inflammatory disease by CD137 costimulation
 Sun,Yonglian;Blink,Sarah E.;Liu,Wenhua;
JOURNAL OF IMMUNOLOGY 177 2 814-821 JUL 15 2006
 18 
197.The role of leukemia-derived B7-H1 (PD-L1) in tumor-T-cell interactions in humans
 Salih,HR;Wintterle,S;Krusch,M;
EXPERIMENTAL HEMATOLOGY 34 7 888-894 JUL 2006

 32 
198.Cutting edge Induction of B7-H4 on APCs through IL-10 Novel suppressive mode for regulatory T cells
 Kryczek,I;Wei,S;Zou,LH;
JOURNAL OF IMMUNOLOGY 177 1 40-44 JUL 1 2006
 191 
199.Reviving exhausted T lymphocytes during chronic virus infection by B7-H1 blockade
 Yao,Sheng;Chen,Lieping
TRENDS IN MOLECULAR MEDICINE 12 6 244-246 JUN 2006

 30 
200.B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma
 Kryczek,I;Zou,L;Rodriguez,P;
JOURNAL OF EXPERIMENTAL MEDICINE 203 4 871-881 APR 17 2006
 417 
201.Renewed interest in cancer immunotherapy with the tumor necrosis factor superfamily molecules
 Tamada,K;Chen,LP
CANCER IMMUNOLOGY IMMUNOTHERAPY 55 4 355-362 APR 2006

 64 
202.Essential role of TNF family molecule LIGHT as a cytokine in the pathogenesis of hepatitis
 Anand,S;Wang,P;Yoshimura,K;
JOURNAL OF CLINICAL INVESTIGATION 116 4 1045-1051 APR 2006
 53 
203.Low surface expression of B7-1 (CD80) is an immunoescape mechanism of colon carcinoma
 Tirapu,I;Huarte,E;Guiducci,C;
CANCER RESEARCH 66 4 2442-2450 FEB 15 2006
 74 
204.Interferon regulatory factor-1 is prerequisite to the constitutive expression and IFN-gamma-induced upregulation of B7-H1 (CD274)
 Lee,SJ;Jang,BC;Lee,SW;
FEBS LETTERS 580 3 755-762 FEB 6 2006
 200 
205.Suppression of human T-cell responses to beta-cells by activation of B7-H4 pathway
 Ou,Dawei;Wangj,Xiaojie;Metzger,Daniel L.;
CELL TRANSPLANTATION 15 5 399-410 2006
 31 
206.The role of leukemia derived B7-H1 in tumor-T-cell interactions in humans.
 Krusch,M;Wintterle,S;Chen,LP;
BLOOD 106 11 220B-220B 子辑 2 4566 NOV 16 2005

207.Costimulatory molecule B7-H1 on primary and metastatic clear cell renal cell carcinoma
 Thompson,RH;Gillett,MD;Cheville,JC;
CANCER 104 10 2084-2091 NOV 15 2005
 115 
208.B7-H1 (CD274) inhibits the development of herpetic stromal keratitis (HSK)
 Jun,H;Seo,SK;Jeong,HY;
FEBS LETTERS 579 27 6259-6264 NOV 7 2005
 25 
209.Renal tubular epithelial cells modulate T-cell responses via ICOS-L and B7-H1
 de Haij,S;Woltman,AM;Trouw,LA;
KIDNEY INTERNATIONAL 68 5 2091-2102 NOV 2005
 29 
210.Constitutive and inducible expression of B7 family of ligands by human airway epithelial cells
 Kim,J;Myers,AC;Chen,LP;
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY 33 3 280-289 SEP 2005
 77 
211.Role of B7-H1 and B7-H4 molecules in down-regulating effector phase of T-cell immunity Novel cancer escaping mechanisms
 Ichikawa,M;Chen,LP
FRONTIERS IN BIOSCIENCE 10 S 2856-2860 SEP 1 2005

 44 212.Expression of functional B7-H2 and B7.2 costimulatory molecules and their prognostic implications in de novo acute myeloid leukemia
 Tamura,H;Dan,K;Tamada,K;
CLINICAL CANCER RESEARCH 11 16 5708-5717 AUG 15 2005
 67 
213.Cigarette smoke extract suppresses human dendritic cell function leading to preferential induction of Th-2 priming
 Vassallo,R;Tamada,K;Lau,JS;
JOURNAL OF IMMUNOLOGY 175 4 2684-2691 AUG 15 2005
 153 
214.Enhancement of CD4 and CD8 immunity by anti-CD137 (4-1BB) monoclonal antibodies during hepatitis C vaccination with recombinant adenovirus
 Arribillaga,L;Sarobe,P;Arina,A;
VACCINE 23 27 3493-3499 MAY 20 2005
 31 
215.In vivo costimulatory role of B7-DC in tuning T helper cell 1 and cytotoxic T lymphocyte responses
 Shin,T;Yoshimura,K;Shin,T;
JOURNAL OF EXPERIMENTAL MEDICINE 201 10 1531-1541 MAY 16 2005
 113 
216.Costimulatory B7-H1 in renal cell carcinoma patients Indicator of tumor aggressiveness and potential therapeutic target
 Thompson,RH;Gillett,MD;Cheville,JC;
JOURNAL OF UROLOGY 173 4 S 169-169 618 APR 2005
 2 
217.Microglial expression of the B7 family member B7 homolog 1 confers strong immune inhibition Implications for immune responses and autoimmunity in the CNS
 Magnus,T;Schreiner,B;Korn,T;
JOURNAL OF NEUROSCIENCE 25 10 2537-2546 MAR 9 2005
 109 
218.B7-H1 co-stimulates the innate and adaptive immunity against Listeria monocytogenes infection
 Choi,IH;Seo,SK;Jeong,HY;
FASEB JOURNAL 19 4 S A906-A906 子辑 1 MAR 4 2005

219.Immunosuppressive network in human tumor environment and its therapeutic relevance
 Zou,WP;Zou,LH;Mottram,P;
FASEB JOURNAL 19 4 S A361-A361 子辑 1 MAR 4 2005
220.
Blockade of B7-H1 and PD-1 by monoclonal antibodies potentiates cancer therapeutic immunity
 Hirano,F;Kaneko,K;Tamura,H;
CANCER RESEARCH 65 3 1089-1096 FEB 1 2005
 565 
221.B7-H3 promotes acute and chronic allograft rejection
 Wang,LQ;Fraser,CC;Kikly,K;
EUROPEAN JOURNAL OF IMMUNOLOGY 35 2 428-438 FEB 2005
 79 

222.Anti-CD137 mAb treatment inhibits experimental autoimmune uveitis by limiting expansion and increasing apoptotic death of uveitogenic T cells
 Shao,H;Fu,YX;Liao,TJ;
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 46 2 596-603 FEB 2005
 24 
223.B7-H4.Ig inhibits human beta-cell destruction mediated by beta cell-specific cytotoxic T cells derived from patients with type 1 diabetes
 Ou,D;Wang,X;Metzger,DL;
DIABETES 54 1 A311-A311 2005
224.The many sounds of T lymphocyte silence
 Melero,I;Arina,A;Chen,LP
IMMUNOLOGIC RESEARCH 33 2 135-147 2005

 5 
225.Cutting edge Cbl-b One of the key molecules tuning CD28- and CTLA-4-Mediated T cell costimulation
 Li,DD;Gal,I;Vermes,C;
JOURNAL OF IMMUNOLOGY 173 12 7135-7139 DEC 15 2004
 71 
226.Costimulatory B7-H1 in renal cell carcinoma patients Indicator of tumor aggressiveness and potential therapeutic target
 Thompson,RH;Gillettt,MD;Cheville,JC;
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101 49 17174-17179 DEC 7 2004
 488 

227.B7-H3 enhances tumor immunity in vivo by costimulating rapid clonal expansion of antigen-specific CD8(+) cytolytic T cells
 Luo,LQ;Chapoval,AI;Flies,DB;
JOURNAL OF IMMUNOLOGY 173 9 5445-5450 NOV 1 2004
 120 
228.Therapeutic efficacy of Muci-specific cytotoxic T lymphocytes and CD137 co-stimulation in a spontaneous mammary cancer model
 Mukherjee,P;Tinder,T;Basu,GD;
JOURNAL OF IMMUNOTHERAPY 27 6 S4-S4 NOV-DEC 2004

229.Interferon-beta enhances monocyte and dendritic cell expression of B7-H1 (PD-L1),a strong inhibitor of autologous T-cell activation relevance for the immune modulatory effect in multiple sclerosis
 Schreiner,B;Mitsdoerffer,M;Kieseier,BC;
JOURNAL OF NEUROIMMUNOLOGY 155 1-2 172-182 OCT 2004
 173 
230.Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
 Curiel,TJ;Coukos,G;Zou,LH;
NATURE MEDICINE 10 9 942-949 SEP 2004

 3,047 
231.已撤回 Immunotherapeutic potential of B7-DC (PD-L2) cross-linking antibody in conferring antitumor immunity (Retracted article. See vol. 70,pg. 9528,2010)
 Radhakrishnan,S;Nguyen,LT;Ciric,B;
CANCER RESEARCH 64 14 4965-4972 JUL 15 2004
 50 
232.Co-signaling molecules of the B7-CD28 family in positive and negative regulation of T lymphocyte responses
 Wang,SD;Chen,LP
MICROBES AND INFECTION 6 8 759-766 JUL 2004

 90 
233.53BP1 is required for class switch recombination
 Ward,IM;Reina-San-Martin,B;Olaru,A;
JOURNAL OF CELL BIOLOGY 165 4 459-464 MAY 24 2004
 209 
234.Improving efficacy of interleukin-12-transfected dendritic cells injected into murine colon cancer with anti-CD137 monoclonal antibodies and alloantigens
 Tirapu,I;Arina,A;Mazzolini,G;
INTERNATIONAL JOURNAL OF CANCER 110 1 51-60 MAY 20 2004
 52 
235.Strong synergy between mutant ras and HPV16 E6/E7 in the development of primary tumors
 Schreiber,K;Cannon,RE;Karrison,T;
ONCOGENE 23 22 3972-3979 MAY 13 2004
 21 
236.Selective suppression of dendritic cell functions by cigarette smoke extract
 Vassallo,R;Chen,LP
 46th Annual Thomas L Petty Aspen Lung Conference Aspen,CO 2003
CHEST 125 5 S 107S-107S MAY 2004
 4 
237.Structural and functional analysis of the costimulatory receptor programmed death-1 (vol 20,pg 337,2004)
 Zhang,XW;Schwartz,JCD;Guo,XL;
IMMUNITY 20 5 651-651 MAY 2004
 2 
238.Co-inhibitory molecules of the B7-CD28 family in the control of T-cell immunity
 Chen,LP
NATURE REVIEWS IMMUNOLOGY 4 5 336-347 MAY 2004

 839 
239.Blockade of B7-H1 suppresses the development of chronic intestinal inflammation
 Totsuka,T;Kanai,T;Uraushihara,K;
GASTROENTEROLOGY 126 4 2 A119-A119 APR 2004
240.Structural and functional analysis of the costimulatory receptor programmed death-1
 Zhang,XW;Schwartz,JCD;Guo,XL;
IMMUNITY 20 3 337-347 MAR 2004
 177 
241.B7-H1 determines accumulation and deletion of intrahepatic CD8(+) T lymphocytes
 Dong,HD;Zhu,GF;Tamada,K;
IMMUNITY 20 3 327-336 MAR 2004
 259 
242.Local expression of B7-H1 promotes organ-specific autoimmunity and transplant rejection
 Subudhi,SK;Zhou,P;Yerian,LM;
JOURNAL OF CLINICAL INVESTIGATION 113 5 694-700 MAR 2004
 144 
243.T Lymphocyte Co-Signaling Pathways of the B7-CD28 Family
 Wang,Shengdian;Chen,Lieping
CELLULAR & MOLECULAR IMMUNOLOGY 1 1 37-42 FEB 2004
 46 
244.New B7 family members with positive and negative costimulatory function
 Rietz,C;Chen,LP
AMERICAN JOURNAL OF TRANSPLANTATION 4 1 8-14 JAN 2004
 27 
245.Ligation of CD 137 receptor prevents and reverses established anergy of CD8(+) cytolytic T lymphocytes in vivo
 Wilcox,RA;Tamada,K;Flies,DB;
BLOOD 103 1 177-184 JAN 1 2004
 74 
246.Control of autoimmune diseases by the B7-CD28 family molecules
 Anand,S;Chen,LP
CURRENT PHARMACEUTICAL DESIGN 10 2 121-128 2004
 12 
247.Blocking the monocyte chemoattractant protein-1/CCR2 chemokine pathway induces permanent survival of islet allografts through a programmed death-1 ligand-1-dependent mechanism
 Lee,I;Wang,LQ;Wells,AD;
JOURNAL OF IMMUNOLOGY 171 12 6929-6935 DEC 15 2003
 88 
248.Expression and role of B7 family molecules,B7-H1 and B7-H2,in patients with acute myeloid leukemia.
 Tamura,H;Ogata,K;Yokose,N;

BLOOD 102 11 234B-234B 子辑 2 4659 NOV 16 2003
249.Expression of the B7-related molecule B7-H1 by glioma cells A potential mechanism of immune paralysis
 Wintterle,S;Schreiner,B;Mitsdoerffer,M;
CANCER RESEARCH 63 21 7462-7467 NOV 1 2003
 258 
250.CD137 signaling interferes with activation and function of CD4(+)CD25(+) regulatory T cells in induced tolerance to experimental autoimmune thyroiditis
 Morris,GP;Chen,LP;Kong,YCM
CELLULAR IMMUNOLOGY 226 1 20-29 NOV 2003
 45