来自西安交通大学附属第一医院肝胆外科的综述论文最近被Hepatogastroenterology接受并在线发表。

文章对氢气医学的研究进行了比较详细的分析，并提出一些新的思路和看法，例如把氢气作为第四种气体信号分子等，提出一些信号通路是氢气作用的重要途径。详细内容可以看全文：

  https://www.hepato-gastroenterology.org/?p=3733

 https://www.hepato-gastroenterology.org/wp-content/uploads/2012/02/11883.pdf

摘要：最近几年一些基础和临床研究表明氢气是一种重要的生理调节因子，在细胞和器官水平上，具有抗氧化、抗炎症、抗凋亡等作用。许多可以使用氢气的途径，例如经过呼吸、注射饱和氢气水，饮用氢气水等。本综述针对最近氢气的一些保护效应和可能的机制，例如作为信号作用的抗氧化能力，抗肿瘤能力等。内源性氢气的效应。并提出一些该领域需要关注的问题和看法。

Hepatogastroenterology. 2012 Feb 10;59(116). doi: 10.5754/hge11883. [Epub ahead of print]

A Review of Hydrogen as a New Medical Therapy.

Zhang JY, Liu C, Zhou L, Qu K, Wang R, Tai MH, Lei Lei JC, Wu QF, Wang ZX.

Abstract

In the past few years many initial and subsequent clinical studies have demonstrated that hydrogen can act as an important physiological regulatory factor to cells and organs on the antioxidant, anti-inflammatory, anti-apoptotic and other protective effects. So far several delivery methods applied in these studies have proved to be available and convenient, including inhalation, drinking hydrogen-dissolved water and injection with hydrogen-saturated saline. This study reviews recent studies on the protectiveness of hydrogen and discusses the possible mechanisms including antioxidant ability as a gaseous signaling molecule, anti-cancer capability and others. It also tries to reveal whether endogenous hydrogen has an important role in the protective system. Nevertheless, there are still many remaining questions in the domain of hydrogen medicine and much work needs to be carried out in the future.