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抑郁症和癌症治疗有希望？

已有 2098 次阅读 2016-8-25 07:51 |个人分类:科学感想|系统分类:博客资讯

抑郁症和癌症治疗有希望？

Depression: A revolution in treatment? - BBC News

Depression: A revolution in treatment? | …

Experimental cancer therapy holds great promise …

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Next Big Future: New method of cancer immunotherapy developed

A team of Stanford ChEM-H scientists has discovered a novel form of cancer immunotherapy, which works by removing certain sugars from the surface of cancer cells and making those cells visible to the immune system. Evidence had been mounting within those few labs that do study the glycocalyx, including Bertozzi’s, that a subset of sugars called sialic acids act as a signal for the innate immune system to ignore the otherwise suspicious-looking tumor. Eliminate those sugars, and maybe innate immune cells would be more likely to recognize and attack the cancer cells, Bertozzi thought. Current immunotherapies on the market work by blocking one of the inhibitory signals that are recognized by the adaptive immune system.

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New drug delivery system slows and controls tumors not aiming for complete elimination

Researchers have created a new drug delivery system that could improve the effectiveness of an emerging concept in cancer treatment - to dramatically slow and control tumors on a long-term, sustained basis, not necessarily aiming for their complete elimination. The approach, called a "metronomic dosage regimen," uses significantly lower doses of chemotherapeutic drugs but at more frequent time intervals. This would have multiple goals of killing cancer cells, creating a hostile biological environment for their growth, reducing toxicity from the drug regimen and avoiding the development of resistance to the cancer drugs being used. A system just published in Chemistry of Materials by a group of researchers from Oregon and the United Kingdom offers an even more effective way to deliver such drugs and may be able to greatly improve this approach, scientists say.

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Fused genes found in esophageal cancer cells offer new clues on disease mechanisms

Despite years of research, cellular mechanisms contributing to cancers like esophageal adenocarcinoma have remained elusive. What has puzzled researchers was how genes in the healthy cells lining the esophagus turned the normal cells into malignant ones. Now, researchers from Case Western Reserve University School of Medicine have characterized structurally abnormal genes in esophageal adenocarcinoma, the findings of which could pave way for developing new biomarkers in this fatal disease. The National Cancer Institute estimates that nearly 37,000 people are living with esophageal cancer in the United States and nearly $1.6 billion is spent on related care each year. In the study published in

Medicalxpress.Com

MSU study: Melatonin may curb breast cancer

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Breakthrough in cancer cell screening advances personalised treatment of childhood leukaemia

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Cancer researchers: It’s time to pay more attention to ‘miracle’ patients

Call it luck - or a medical miracle. During clinical trials for experimental cancer drugs, some patients simply respond better than others. And a tiny fraction of patients see dramatic results, responding so well to treatment that they survive forms of cancers that quickly kill their counterparts. Stories about people like Emily Whitehead, the then-6-year-old who was enrolled in a clinical trial that saved her life, make headlines. But statistically speaking, they’re insignificant, mere outliers. Because they deviate so far from the norm, these “exceptional responders” are often overlooked by researchers. Not so fast, says Eric Perakslis. Perakslis, who heads up pharmaceutical giant Takeda's

Washington Post

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Eating Plants To Fight Cancer

A study published in 2015 in the journal Cancer revealed that eating a plant-based diet and avoiding meat and dairy can reduce a person's risk of cancer or cancer recurrence. Nutrients in leafy green vegetables and whole grains are thought to be especially protective. In addition, increasing low sugar fruits, vegetables and fiber while reducing fat, sodium and added sugar is particularly important for cancer survivors, according to the study's author, Fang Fang Zhang, M.D., Ph.D. Dr. Neal Barnard and colleagues at the Physicians Committee for Responsible Medicine created a list of principles to follow for optimal cancer prevention. This was published in the Journal of the American College of

The Huffington Post

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How a nasty, brain-eating parasite could help us fight cancer

We've known since the turn of the 20th century that some infectious diseases are a major risk for developing specific cancers. More worryingly, about one-sixth of cancers worldwide are attributable to infectious agents. Globally, more than 2m cancer cases are linked to certain carcinogenic viral, bacterial or parasitic agents. Two-thirds of these occur in developing countries. Although we've been aware of the connection between parasites and cancer since before the 18th century, we're increasingly linking certain parasites to an increased risk of developing specific forms of cancer. For example, the fish-borne parasitic worms Opisthorchis viverrini and Clonorchis sinensis have been linked to

Medicalxpress.Com

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Majority of cancers can be caused by infectious agents in sub-Saharan Africa, reveals study

In 1963, Irish surgeon Denis Parson Burkitt airmailed samples of an unusual jaw tumor found in Ugandan children to his colleague, Anthony Epstein, at Middlesex Hospital in London. Epstein, an expert in chicken viruses and an early adopter of the electron microscope, cultured the tissue and took a look. What he found has become known as Epstein-Barr virus, the cause of mononucleosis, the "kissing cold", and also, it turns out, an ingredient of the jaw tumor in which it was originally found, now known as Burkitt's lymphoma. "Just imagine the process of shipping tissue samples from Uganda to England in the early 1960s!" says Rosemary Rochford, PhD, investigator at the University of Colorado Cancer Center, professor in the CU School of Medicine Department of Immunology and Microbiology, and author of a new study in the journal Current Opinions in Virology exploring the modern contribution of viruses to cancer in sub-Saharan Africa.

News-Medical-Net

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Researchers find new way for early prediction of leukemic relapse

Researchers at University of California San Diego School of Medicine and Moores Cancer Center have identified RNA-based biomarkers that distinguish between normal, aging hematopoietic stem cells and leukemia stem cells associated with secondary acute myeloid leukemia (sAML), a particularly problematic disease that typically afflicts older patients who have often already experienced a bout with cancer. The findings, published online August 25 in Cell Stem Cell, suggest a new way to predict leukemic relapse early and to identify potential targets for new drug development. Secondary AML typically follows a chronic pre-malignant disease or treatment for other cancers. Consequently, patients tend

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