人造甜味剂可以在保持甜味的同时减少添加糖量和卡路里摄入。但是，3月24日在PLOS Medicine上发表的一项研究表明，癌症风险增加与某些人造甜味剂食用有关联。研究人员发现，食用大量人工甜味剂（尤其是阿斯巴甜（aspartame）和乙酰磺胺酮-K（acesulfame-K））的受试者比非使用者患癌风险高。其中，乳腺癌和肥胖相关癌症的风险较高。

Study suggests association between consuming artificial sweeteners and increased cancer risk

https://www.sciencedaily.com/releases/2022/03/220324143800.htm

Charlotte Debras, Eloi Chazelas, Bernard Srour, Nathalie Druesne-Pecollo, Younes Esseddik, Fabien Szabo de Edelenyi, Cédric Agaësse, Alexandre De Sa, Rebecca Lutchia, Stéphane Gigandet, Inge Huybrechts, Chantal Julia, Emmanuelle Kesse-Guyot, Benjamin Allès, Valentina A. Andreeva, Pilar Galan, Serge Hercberg, Mélanie Deschasaux-Tanguy, Mathilde Touvier. Artificial sweeteners and cancer risk: Results from the NutriNet-Santé population-based cohort study. PLOS Medicine, March 24, 2022; DOI: 10.1371/journal.pmed.1003950