一项新研究表明，长期食用高脂肪和高糖的西式饮食（肥胖通常是由于饮食中富含脂肪和糖。）会损害肠道的免疫系统，从而增加炎症性肠病或肠道感染风险。

Western diet may increase risk of gut inflammation, infection: Diet rich in sugar, fat damages immune cells in digestive tracts of mice -- ScienceDaily

1. Ta-Chiang Liu, Justin T. Kern, Umang Jain, Naomi M. Sonnek, Shanshan Xiong, Katherine F. Simpson, Kelli L. VanDussen, Emma S. Winkler, Talin Haritunians, Atika Malique, Qiuhe Lu, Yo Sasaki, Chad Storer, Michael S. Diamond, Richard D. Head, Dermot P.B. McGovern, Thaddeus S. Stappenbeck. Western diet induces Paneth cell defects through microbiome alterations and farnesoid X receptor and type I interferon activation. Cell Host & Microbe, 2021; DOI: 10.1016/j.chom.2021.04.004

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