常见食品添加剂影响肠道微生物群

食品添加剂E171（二氧化钛纳米颗粒）在食品和一些药物中作为增白剂被大量使用。在超过900种食品中，如口香糖和蛋黄酱中，E171每天被普通人消耗的比例很高。

悉尼大学的研究提供了新的证据，证明纳米颗粒存在于许多食品中，可能对人体健康产生重大和有害的影响。这项发表在《营养学前沿》杂志上的小鼠研究发现，食用含有E171的食物会影响肠道微生物群（由肠道内数万亿细菌定义），从而引发炎症性肠病和结直肠癌等疾病。

Common food additive found to affect gut microbiota

https://www.sciencedaily.com/releases/2019/05/190513123017.htm

Journal Reference:

1. gabriela V. Pinget, Jian K. Tan, Bartlomiej Janac, Nadeem O. Kaakoush, Alexandra Angelatos, John O'sullivan, Yen Koay, Frederic Sierro, Shiva Divakarla, Robert J. Moore, Dragana Stanley, Wojciech Chrzanowski, and Laurence Macia. Impact of the food additive titanium dioxide (E171) on gut microbiota-host interaction. Frontiers in Nutrition, 2019 DOI: 10.3389/fnut.2019.00057

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用器官芯片技术在体外进行人体肠道微生物生理学研究

Human gut microbiome physiology can now be studied in vitro using Organ Chip technology

https://www.sciencedaily.com/releases/2019/05/190513143838.htm

Journal Reference:

1. Sasan Jalili-Firoozinezhad, Francesca S. Gazzaniga, Elizabeth L. Calamari, Diogo M. Camacho, Cicely W. Fadel, Amir Bein, Ben Swenor, Bret Nestor, Michael J. Cronce, Alessio Tovaglieri, Oren Levy, Katherine E. Gregory, David T. Breault, Joaquim M. S. Cabral, Dennis L. Kasper, Richard Novak, Donald E. Ingber. A complex human gut microbiome cultured in an anaerobic intestine-on-a-chip. Nature Biomedical Engineering, May 13, 2019; DOI: 10.1038/s41551-019-0397-0