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发现一种细菌蛋白能促进癌症发生
------研究表明细菌感染可能导致比先前认为的更多的癌症
研究人员发现,DnaK,一种细菌支原体的蛋白质,干扰了支原体感染细胞对DNA损伤的反应和修复能力,DNA损伤是癌症的已知来源。
https://www.sciencedaily.com/releases/2018/12/181204155158.htm
Journal Reference:
Davide Zella, Sabrina Curreli, Francesca Benedetti, Selvi Krishnan, Fiorenza Cocchi, Olga S. Latinovic, Frank Denaro, Fabio Romerio, Muhammad Djavani, Man E. Charurat, Joseph L. Bryant, Hervé Tettelin, Robert C. Gallo. Mycoplasma promotes malignant transformation in vivo, and its DnaK, a bacterial chaperon protein, has broad oncogenic properties. Proceedings of the National Academy of Sciences, 2018; 201815660 DOI: 10.1073/pnas.1815660115
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