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DNA合成突破将加速医药、生物燃料和农业开发(外一)

已有 1642 次阅读 2018-6-25 17:25 |个人分类:科学感想|系统分类:博客资讯

DNA合成突破将加速医药、生物燃料和农业开发


The Institute's approach shakes things up by relying on an enzyme from the immune system, terminal deoxynucleotidyl transferase, that writes fresh DNA instead of copying it. If you tie a nucleotide (the unit that forms the polymers in DNA) to each enzyme with a cleavable linker, you can have the enzyme produce DNA sequences very quickly at about 200 bases per minute. You'll also know what you should get, so there should be fewer costly errors.

This is far from ready for prime time. It has a lower yield of useful material than conventional techniques (98 percent versus 99.5 percent), and it has yet to produce large-scale genes. It could dramatically alter genetic research if the scientists make further progress, though. If you could synthesize even a complex gene within hours, you could quickly develop medicines, biofuels (the lab team's focus) or agriculture. It could lower the costs, too, by reducing mistakes and speeding up the time to market. And of course, it could improve the overall rate of discovery, helping scientists spend less time waiting for synthesis and more time taking advantage of what they've created.

见:

DNA synthesis breakthrough could lead to faster medical discoveries

DNA synthesis breakthrough could lead to faster medical ...

Engadget

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细胞大小的“微激光”可以调节大脑活动


Cell-sized 'microlasers' could regulate brain activity

Cell-sized 'microlasers' could regulate brain activity

Engadget




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