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研究人员发现可同时作为肿瘤抑制因子和转移驱动因子蛋白(外2)

已有 1781 次阅读 2018-2-28 08:01 |个人分类:科学感想|系统分类:博客资讯

研究人员发现蛋白质既可以作为肿瘤抑制因子,又可以作为转移的驱动因子


Nicolas Aznar et al, Convergence of Wnt, growth factor, and heterotrimeric G protein signals on the guanine nucleotide exchange factor Daple, Science Signaling (2018).  DOI: 10.1126/scisignal.aao4220

见:

Researchers find protein that acts both as tumor suppressor and as driver of metastasis

https://medicalxpress.com/news/2018-02-protein-tumor-suppressor-driver-metastasis.html

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除铁可作为一种潜在的癌症治疗方法


Takayuki Ninomiya et al. Iron depletion is a novel therapeutic strategy to target cancer stem cells, Oncotarget (2017). DOI: 10.18632/oncotarget.21846

见:

Iron removal as a potential cancer therapy

https://medicalxpress.com/news/2018-02-iron-potential-cancer-therapy.html

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开启生存信号驱动抗药性


Abbie E. Fearon et al, PHLDA1 Mediates Drug Resistance in Receptor Tyrosine Kinase-Driven Cancer, Cell Reports (2018).  DOI: 10.1016/j.celrep.2018.02.028

见:

Switching on survival signalling to drive drug resistance

https://medicalxpress.com/news/2018-02-survival-drug-resistance.html

 




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