SAN DIEGO - Dennis Lyon was a genetic train wreck. Cancer was ravaging his liver, lungs, bones and brain, and tests showed so many tumor mutations that drugs targeting one or two wouldn’t do much good. It seemed like very bad news, yet his doctors were encouraged. The reason: People with the most messed-up genes often are the ones who do best on treatments that enlist the immune system. “These are the patients we used to be very depressed about,” thinking they couldn’t be helped, said Dr. Razelle Kurzrock at the University of California, San Diego. “Now when we see those types of patients, we’re really excited,” because there are so many ways for the immune system to recognize the cancer cells
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MIT工程师设计更有效的信使RNA转移方法
ScienceNews-Medical-Net
MIT engineers design more effective synthetic mRNA delivery systemBy delivering strands of genetic material known as messenger RNA (mRNA) into cells, researchers can induce the cells to produce any protein encoded by the mRNA. Now, a team of MIT chemical engineers, inspired by the way that cells translate their own mRNA