Summary: A lack of adaptability in hippocampal place cells could be key to memory deficits in schizophrenia, researchers report. A team of Columbia scientists has found that disruptions to the brain’s center for spatial navigation - its internal GPS - result in some of the severe memory deficits seen in schizophrenia. The new study in mouse models of the
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研究人员发现与2型糖尿病和冠心病风险相关的基因变异
Researchers identify gene variants linked to both type 2 diabetes and CHD risk
Type 2 diabetes (T2D) has become a global epidemic affecting more than 380 million people worldwide; yet there are knowledge gaps in understanding the etiology of type-2 diabetes. T2D is also a significant risk factor for coronary heart disease (CHD), but the biological pathways that explain the connection have remained somewhat murky. Now, in a large analysis of genetic data, published on August 28, 2017 in Nature Genetics, a team, led by researchers in the Perelman School of Medicine at the University of Pennsylvania, has first looked into what causes T2D and second clarified how T2D and CHD - the two diseases that are the leading cause of global morbidity and mortality, are linked. Examining