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鉴于公众担心转基因食品的健康安全问题,而CRISPR基因编辑被认为是没有引入外源基因,只是编辑或切除自身的基因,因此,理论上不存在可担心的安全问题。美国似已不再对CRISPR基因编辑产品进行监管,如以前一段时间的一个新闻《Nature:CRISPR编辑的蘑菇也不用监管了》、《Gene-edited CRISPR mushroom escapes US regulation...》。
因此,生物技术公司巨头孟山都公司转向利用CRISPR-Cas genome-editing technology进行作物遗传修饰。
Science
Monsanto cuts deal to use CRISPR to engineer food
Here come the CRISPR-crops. Agricultural biotech heavyweight Monsanto has licensed the use of CRISPR-Cas genome-editing technology from the Broad Institute at Harvard University and MIT. Monsanto intends to use CRISPR to make crops like corn and soybeans more fruitful and more resistant to diseases and drought, says Tom Adams, Monsanto’s head of biotechnology. “Getting more productivity out of less acres with less inputs is clearly a critical thing for humanity,” he says. “And gene editing is another tool that can help us accelerate that.” CRISPR allows researchers to remove and replace bits of DNA in a much more targeted way than previous genetic modification techniques. That precision makes
New Scientist
Monsanto Nets First CRISPR License to Modify Crops--with Key Restrictions
与此形成鲜明对比的是,一项针对GMO作物的长期研究结果对转基因技术并不有利。
Health
Longest Study of GMO Crops Ever Yields Surprising Results
American researchers have completed the longest study of popular agricultural genetically modified organisms (GMOs) to date. The 14-year study found that GMO crops increased the use of herbicides on American farms by 28 percent. The study examined data from 5,000 soybean and 5,000 maize farmers in the United States. The GMO soybean and maize farms each comprised two GMO varieties - one pest-resistant variety, and one herbicide-tolerant variety. The researchers found that while the use of insecticides decreased by about 11 percent on GMO farms due to the pest-resistant varieties of the crops themselves, use of herbicides, mainly glyphosate marketed by Monsanto as Roundup, increased by more than twice
Organic Authority
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