该专题主要讨论的话题为“垂体肿瘤的基础与临床”，共有五篇论文，主要来自华中科技大学同济医院雷霆教授团队，德国Tübingen大学Jürgen Honegger教授团队，德国Philipps-Universität Marburg大学Jörg W. Bartsch教授团队的研究成果。该专题涵盖了垂体肿瘤的最新研究和进展，旨在为临床医生和研究人员提供宝贵的信息和观点。

我们相信这些论文将为垂体肿瘤领域的研究和实践带来新的见解和启发。感谢所有作者和审稿人的辛勤工作，也感谢所有读者的支持。我们期待着在这个领域继续见证更多的突破和进步！

专题文章

Overview of the 2022 WHO Classification of Pituitary Adenomas/Pituitary Neuroendocrine Tumors: Clinical Practices, Controversies, and Perspectives

作者：Xue-yan Wan, Juan Chen, Ting Lei

DOI：10.1007/s11596-022-2673-6

摘要：The latest edition of the WHO classification of the central nervous system was published in 2021. This review summarizes the major revisions to the classification of anterior pituitary tumors. The most important revision involves preferring the terminology of pituitary neuroendocrine tumor (PitNET), even though the terminology of pituitary adenoma (PA) still can be used according to this WHO classification compared to the previous one……

推荐语：对2022年世界卫生组织（WHO）垂体腺瘤/垂体神经内分泌肿瘤分类进行了概述，并探讨了临床实践中的争议和未来展望。

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Surgical Treatment of Craniopharyngiomas in Adults: Comparison between Primary Surgery and Surgery for Recurrence

作者：Rocío Evangelista Zamora, Florian Grimm, Jürgen Honegger

DOI：10.1007/s11596-022-2679-0

摘要：Objective:Few studies have investigated the differences in outcomes between primary and repeat surgery for a craniopharyngioma in adults. As a result, a treatment concept for adult patients with a craniopharyngioma has not yet been established……

推荐语：比较了成人颅咽管瘤的初次手术和复发手术的治疗效果，为临床医生提供了重要的参考信息。

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MicroRNA-149 Regulates Proliferation, Migration, and Invasion of Pituitary Adenoma Cells by Targeting ADAM12 and MMP14

作者：Zhuo Zhang, Agnes Schäfer, Jörg W. Bartsch

DOI：10.1007/s11596-022-2676-3

摘要：Objective:Pituitary adenomas (PAs) can adapt an aggressive phenotype by invading adjacent brain structures with rapid cellular proliferation. Previous studies demonstrated that excessive expression of metalloproteases ADAM12 and MMP-14 is instrumental for the active proliferation and invasiveness of PA cells in vitro and of tumors in vivo.……

推荐语：研究了微小RNA-149对垂体腺瘤细胞增殖、迁移和侵袭的调控作用，并揭示了其潜在的作用机制。

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Surgical Technique and Efficacy Analysis of Extra-pseudocapsular Transnasal Transsphenoidal Surgery for Pituitary Microprolactinoma

作者：Xue-yan Wan, Lin-han Li, Ting Lei

DOI：10.1007/s11596-022-2678-1

摘要：Objective:To elucidate the role of transsphenoidal surgery in the treatment of pituitary microprolactinoma.Methods:The clinical data of 107 prolactinoma cases treated by extra-pseudocapsular transnasal transsphenoidal surgery (ETTS) for different indications in our department since 2011 was retrospectively analyzed.……

推荐语：探讨了额外假囊性经鼻蝶窦手术在垂体微泌乳素瘤治疗中的手术技术和疗效分析。

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Extra-pseudocapsular Transnasal Transsphenoidal Resection of Pituitary Macroadenoma: Technique Note and Evaluation of Endocrine Function

作者：Yu Xu, Xue-yan Wan, Ting Lei

DOI：10.1007/s11596-022-2674-5

摘要：Objective:In this study, we investigated the surgical technique and endocrine assessment of pituitary function of patients with macroadenoma treated by extra-pseudocapsular transnasal transsphenoidal surgery (ETTS).……

推荐语：介绍了额外假囊性经鼻蝶窦切除垂体大腺瘤的手术技术，并评估了内分泌功能的恢复情况。

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