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MCE 国际站:cis-Vaccenic acid
中文名:十八烷酸
CAS:506-17-2
品牌:MedChemExpress (MCE)
存储条件:Solution, -20°C, 2 years
生物活性:cis-Vaccenic acid 是 Rhodopseudomonas capsulate 的抗病毒提取物,也是 Rhodopseudomonas capsulate[1] 的主要活性成分,是一种潜在的胎儿血红蛋白诱导剂[2] .
体外:顺式-Vaccenic acid (CVA)(50 μM、70 μM 和 100 μM)在 K562、JK1 和转基因小鼠红细胞祖细胞[2]中诱导分化并上调γ珠蛋白合成。 cis-Vaccenic acid (50 μM) 也增加联苯胺阳性 JK-1 细胞的百分比[2]。
热销产品:4-Chloro-7H-pyrrolo[2,3-d]pyrimidine | SPB | Tamibarotene | CITCO | Relugolix | Cefoperazone | LCMV gp33-41 | H-Phe(4-Ac)-OH | 3-Nitropropanoic acid | Demeclocycline
研究领域:Anti-infection
作用靶点:Antibiotic
Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
参考文献:[1]. H Hirotani, et al. Inactivation of T5 phage by cis-vaccenic acid, an antivirus substance from Rhodopseudomonas capsulata, and by unsaturated fatty acids and related alcohols. FEMS Microbiol Lett. 1991 Jan 1;61(1):13-7.
[2]. Idowu A Aimola, et al. Cis-vaccenic acid induces differentiation and up-regulates gamma globin synthesis in K562, JK1 and transgenic mice erythroid progenitor stem cells. Eur J Pharmacol. 2016 Apr 5;776:9-18.
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