3-Nitropropanoic acid | 3-硝基丙酸

MCE 国际站：3-Nitropropanoic acid

中文名：3-硝基丙酸

CAS：504-88-1

品牌：MedChemExpress (MCE)

存储条件：4°C, sealed storage, away from moisture and light

生物活性： 3-硝基丙酸 (β-Nitropropionic acid) 是 succinate dehydrogenase 的不可逆抑制剂。 3-Nitropropanoic acid 具有强大的抗分枝杆菌活性，MIC 值为 3.3 μM^[1][2]。 IC50 和目标：琥珀酸脱氢酶^[1]

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研究领域：Anti-infection  |  Apoptosis

作用靶点：Bacterial  |  Apoptosis

Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Fluorescent Dye  |  PROTAC  |  Isotope-Labeled Compounds  |  Oligonucleotides

参考文献：[1]. Chomcheon P, et al. 3-Nitropropionic acid (3-NPA), a potent antimycobacterial agent from endophytic fungi: is 3-NPA in some plants produced by endophytes? J Nat Prod. 2005 Jul;68(7):1103-5.

[2]. Huang LS, et al. 3-nitropropionic acid is a suicide inhibitor of mitochondrial respiration that, upon oxidation by complex II, forms a covalent adduct with a catalytic base arginine in the active site of the enzyme. J Biol Chem. 2006 Mar 3;281(9):5965-72.