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MCE 国际站:Triton X-100
中文名:曲拉通X-100
CAS:9002-93-1
品牌:MedChemExpress (MCE)
存储条件:Pure form: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
生物活性:Triton X-100 是一种非变性洗涤剂,可溶解脂质膜。 Triton X-100 通常用于实验室,并应用于制造过程不同阶段的疫苗。 Triton X-100 被列为某些疫苗的赋形剂,包括裂解病毒流感疫苗。 Triton X-100 是一种非离子表面活性剂[1][2]。
体外:Triton X-100 (0.5%-0.05%,1 小时) 可降低西尼罗河病毒 (WNV) 等经典包膜病毒的感染性[3]。 Triton X-100 (0.19-0.20 mM) 使 HeLa 细胞发生不可逆的膜透化和结构塌陷[4]。 Triton X-100 (0.01%,1 小时) 诱导前列腺和结肠癌细胞系 (PC-3、SW-620 和 HT-29 细胞) 凋亡和坏死,其特征是典型的形态学特征和核小体间 DNA 碎片[5]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only.
热销产品:WNK463 | Semaglutide (TFA) | Eriodictyol | Elaiophylin | Hydroxysafflor yellow A | Clopidogrel | Diosmetin | Tariquidar | Rhodamine 123 | DPPC
研究领域:Others
作用靶点:Biochemical Assay Reagents
Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
参考文献:[1]. Herman SM, et al. The hidden allergen: Triton X-100, a derivative of polyethylene glycol. J Allergy Clin Immunol Pract. 2021;9(7):2941.
[2]. Ghosh R, et al. Unraveling diverse action of triton X-100 and methimazole on lysozyme fibrillation/aggregation: Physicochemical insights. Int J Biol Macromol. 2021;167:736-745.
[3]. Colavita F, et al. Evaluation of the inactivation effect of Triton X-100 on Ebola virus infectivity. J Clin Virol. 2017 Jan;86:27-30.
[4]. Koley D, et al. Triton X-100 concentration effects on membrane permeability of a single HeLa cell by scanning electrochemical microscopy (SECM). Proc Natl Acad Sci U S A. 2010 Sep 28;107(39):16783-7.
[5]. Borner MM, et alE. The detergent Triton X-100 induces a death pattern in human carcinoma cell lines that resembles cytotoxic lymphocyte-induced apoptosis. FEBS Lett. 1994 Oct 17;353(2):129-32.
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