Concanavalin A | 伴刀豆球蛋白A

MCE 国际站：Concanavalin A

中文名：伴刀豆球蛋白A

CAS：11028-71-0

品牌：MedChemExpress (MCE)

存储条件：Powder: -80°C, 2 years; -20°C, 1 year.In solvent: -80°C, 6 months; -20°C, 1 month.

生物活性： Concanavalin A 是一种 Ca²⁺/Mn²⁺ 依赖性甘露糖/葡萄糖结合植物凝集素，存在于刀豆中。 Concanavalin A可诱导程序性细胞死亡^[1]。

体内：Concanavalin A (20 mg/kg; i.v.) 诱导小鼠自身免疫性肝炎[3]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: 6-8 weeks, 20 g Male Balb/c mice[3] Dosage: 20 mg/kg Administration: I.v. Result: Increased the ALT and AST levels after 8 hours.

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研究领域：Anti-infection  |  Apoptosis

作用靶点：Antibiotic  |  Apoptosis

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参考文献：[1]. Li W, et, al. Concanavalin A: a potential anti-neoplastic agent targeting apoptosis, autophagy and anti-angiogenesis for cancer therapeutics. Biochem Biophys Res Commun. 2011 Oct 22;414(2):282-6. 

[2]. Cantelli A, et, al. Concanavalin A-Rose Bengal bioconjugate for targeted Gram-negative antimicrobial photodynamic therapy. J Photochem Photobiol B. 2020 Mar 13;206:111852. 

[3]. Zhou Y, et al. The Protective Effect of Resveratrol on Concanavalin-A-Induced Acute Hepatic Injury in Mice. Gastroenterol Res Pract. 2015;2015:506390.