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MCE 国际站:Osanetant
CAS:160492-56-8
品牌:MedChemExpress (MCE)
存储条件:Powder: -20°C, 3 years.In solvent: -80°C, 6 months; -20°C, 1 month.
生物活性:Osanetant (SR142801) 是一种选择性的 NK3 受体 拮抗剂。 Osanetant 具有类似抗焦虑和抗抑郁的作用,用于治疗精神分裂症[1]。
体内:Osanetant(SR142801;口服;1-10 mg/kg;测试前 60 分钟)显着增加社交互动时间[1] .Osanetant(ip;5 和 10 mg/kg;测试前 30 分钟)减少不动时间[1]。
(S,R,S)-AHPC-Me (hydrochloride) | DSRM-3716 | Sodium 2-oxopropanoate | RBN012759 | Procyanidin A1 | Biotin-PEG12-NHS ester | Curzerene | PP1 | AZ10606120 (dihydrochloride) | Thiazole Orange
研究领域:GPCR/G Protein | Neuronal Signaling
作用靶点:Neurokinin Receptor
Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
参考文献:[1]. Salomé N, et al. Selective blockade of NK2 or NK3 receptors produces anxiolytic- and antidepressant-like effects in gerbils. Pharmacol Biochem Behav. 2006 Apr;83(4):533-9.
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