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MCE 国际站:Nirsevimab
CAS:1989556-22-0
品牌:MedChemExpress (MCE)
存储条件:Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性:Nirsevimab (MEDI8897) 是一种重组人呼吸道合胞病毒 (RSV) 单克隆抗体,具有修饰的 Fc 区,可延长其半衰期。Nirsevimab 对 RSV-B 具有亲和力,Kd 值为 1.5 nM。Nirsevimab 可用于 RSV 研究。
热销产品:AF64394 | Sarilumab | Vandetanib | 3-Deazaadenosine | CID755673 | Cisatracurium (besylate) | StemRegenin 1 | Masitinib (mesylate) | Pregnenolone | BJE6-106
研究领域:Anti-infection
作用靶点:RSV
Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
参考文献:[1]. Griffin MP, et al. Single-Dose Nirsevimab for Prevention of RSV in Preterm Infants. N Engl J Med. 2020 Jul 30;383(5):415-425. [2]. Griffin MP, et al. Safety, Tolerability, and Pharmacokinetics of MEDI8897, the Respiratory Syncytial Virus Prefusion F-Targeting Monoclonal Antibody with an Extended Half-Life, in Healthy Adults. Antimicrob Agents Chemother. 2017 Feb 23;61(3):e01714-16. [3]. Cabán M, et al. Cross-protective antibodies against common endemic respiratory viruses. Nat Commun. 2023 Feb 13;14(1):798.
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