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国际站:Teduglutide
CAS:197922-42-2
品牌:MedChemExpress (MCE)
存储条件:Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性: Teduglutide 是一种二肽基肽酶 IV 抗性胰高血糖素样肽 2 (GLP-2) 类似物。 Teduglutide 与肠粘膜的营养作用有关。替度鲁肽可用于短肠综合征(SBS)和克罗恩病(CD)的研究[1][2]。
参考文献:[1]. Buchman AL, et al; Teduglutide Study Group. Teduglutide, a novel mucosally active analog of glucagon-like peptide-2 (GLP-2) for the treatment of moderate to severe Crohn's disease. Inflamm Bowel Dis. 2010 Jun;16(6):962-73.[2]. Jeppesen PB, et al. Teduglutide (ALX-0600), a dipeptidyl peptidase IV resistant glucagon-like peptide 2 analogue, improves intestinal function in short bowel syndrome patients. Gut. 2005 Sep;54(9):1224-31.
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