|
国际站:Evolocumab
CAS:1256937-27-5
品牌:MedChemExpress (MCE)
存储条件:Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性:Evolocumab (AMG 145) 是一种人单克隆抗体,可抑制 PCSK9。 Evolocumab 与循环的 PCSK9 蛋白结合,抑制其与 LDLR 结合。 Evolocumab可用于高胆固醇血症和动脉粥样硬化性心血管疾病的研究[1]。 IC50 和目标:PCSK9[1]
参考文献:[1]. Fala L, et, al. Repatha (Evolocumab): Second PCSK9 Inhibitor Approved by the FDA for Patients with Familial Hypercholesterolemia. Am Health Drug Benefits. 2016 Mar;9(Spec Feature):136-9.
Archiver|手机版|科学网 ( 京ICP备07017567号-12 )
GMT+8, 2024-7-17 06:45
Powered by ScienceNet.cn
Copyright © 2007- 中国科学报社