A. Sequencing reads containing the 17 non-synonymous SNPs have an average of >99% identity with mouse, and less to human. In all cases the “cancer causing” SNP matches to mouse gene sequence.B. Sequencing reads harbouring the CCND2 SNP revealed the existence of more than 15 single nucleotide variants which are common between different data sets and each of which matches to mouse reference.C. The number of SNPs fell to zero in most cases after removing mouse sequencesD. No cancer related mutations detected in human naïve cells.
