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第一作者:Yu Ling
第一单位:广东海洋大学
第一通讯:Magdy M. Mahfouz
Abstract
背景1:The molecular responses of plants to the important abiotic stress, heat stress (HS), have been extensively studied at the transcriptional level. 背景2:Alternative splicing (AS) is a post-transcriptional regulatory process in which an intron-containing gene can generate more than one mRNA variant. 提出问题:The impact of HS on the pre-mRNA splicing process has been reported in various eukaryotes but seldom discussed in-depth, especially in plants. 主要内容:Here, we review AS regulation in response to HS in different plant species. We discuss potential molecular mechanisms controlling heat-inducible AS regulation in plants and hypothesize that AS regulation participates in heat-priming establishment and HS memory maintenance. 结论:We propose that the pre-mRNA splicing variation is an important regulator of plant HS responses (HSRs). 摘 要
植物对于热胁迫等非生物胁迫的分子响应在转录层面已经有了广泛的研究。可变剪切是一种转录后的调控机制,含有内含子的基因可以通过可变剪切产生超过一个mRNA变体。前体mRNA剪切过程中可变剪切的影响在各种真核生物中已有广泛报道,但很少被深入地讨论,尤其是在植物中。本文中,作者综述了不同植物物种对于高温胁迫的可变剪切调节。作者讨论了植物中控制热诱导可变剪切调节的潜在分子机制,并假设可变剪切调节参与了植物中的热启动建立和热胁迫记忆维持。作者提出,前体mRNA剪接变异是植物热胁迫响应的重要调控因子。
通讯作者
** Magdy M. Mahfouz **
个人简介: 1997年,埃及开罗大学,硕士; 2004年,俄亥俄州立大学,博士。 研究方向:为基础生物学和生物技术开发基因组工程技术。
doi: https://doi.org/10.1016/j.tplants.2021.07.008
Journal: Trends in Plant Science
Published date: July 29, 2021
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