RALF-FERONIA signaling: linking plant immune response with cell growth

第一作者：Xin Zhang

第一单位：湖南大学

通讯作者：Feng Yu

 Abstract 

Plants perceive various external or internal signals to self-modulate biological processes through members of the Receptor-like kinases (RLKs) family, among which, Catharanthus roseus receptor-like kinase 1-like (CrRLK1L) proteins with their ligand Rapid Alkalinization Factor (RALF) peptides have attracted considerable interest. FERONIA (FER), a CrRLK1L member, was initially found to act as a major plant cell growth modulator in distinct tissues. Later, the RALF-FER pathway was confirmed to serve as an essential regulator of plant stress responses, including but not limited to immune responses. Furthermore, the RALF-FER pathway modulates immune responses and cell growth in a context-specific manner, and the vital roles of this pathway are beginning to be appreciated in crop species. The recent remarkable advances in understanding the functions and molecular mechanisms of the RALF-FER pathway have also raised many interesting questions that need to be answered in the future. This review mainly focuses on the roles of FER, and other CrRLK1L members as appropriate, in modulating immune responses in the context of cell growth in response to their RALF peptide ligands and presents a brief outlook for future research.

 摘  要 

植物通过类受体激酶RLKs感知多种外部和内部信号来自我调整生物学进程，其中，长春花类受体激酶CrRLK1L蛋白与其配体快速碱化因子RALF多肽吸引了众多研究者的目光。CrRLK1L的一个成员FERONIA蛋白最早被发现作为植物生长的主要调控因子，在各个组织中均发挥作用。其后，研究人员确认了RALF-FER通路是植物胁迫响应的主要调控因子，包括但不限制于免疫响应。此外，RALF-FER通路会根据自身情况来调控免疫响应和细胞生长，并且有关该通路在作物的研究也越来越受到重视。最近有关RALF-FER通路的功能和分子机制的突破性研究进展同样也引出了许多在将来亟待解决的一些新的问题。本综述主要关注了FER及其它CrRLK1L蛋白的功能，包括响应于其配体RALF多肽来在细胞生长过程中调控免疫应答，并且对未来相关研究提出了简要的展望。

 通讯作者 

doi: 10.1016/j.xplc.2020.100084

Journal: Plant Communications

Published date: June 11, 2020