COP1‐ and BBXs‐HY5‐Mediated Light Signal Transduction in Plants

First author: Dongqing Xu; Affiliations: Nanjing Agricultural University (南京农业大学): Nanjing, China

Corresponding author: Dongqing Xu

Light is one of the most essential environmental factors affecting many aspects of growth and developmental processes in plants. Plants undergo skotomorphogenic or photomorphogenic development dependent on the absence or presence of light. These two developmental programs enable a germinated seed to become a healthy seedling at the early stage of the plant life cycle. CULLIN 4 (CUL4)‐DNA DAMAGE‐BINDING PROTEIN 1 (DDB1)‐based COSTITUTIVELY PHOTOMORPHOGENIC 1‐ SUPPRESSOR OF PHYA (COP1‐SPA) and COP10‐DEETIOLATED 1 (DET1)‐DDB1 (CDD) E3 ubiquitin ligase complexes promote the skotomorphogenesis by ubiquitinating and degrading a number of photomorphogenic‐promoting factors in darkness. Photoreceptors sense and transduce light information to downstream signaling, thereby initiating a set of molecular events and subsequent photomorphogenesis. These processes are precisely modulated by a group of components including various photoreceptors, E3 ubiquitin ligase, and transcription factors at the molecular level. In this review, I provide an overview of the current understanding of COP1‐, ELOGATED HYPOCORYL 5 (HY5)‐ and B‐BOX CONTAINING PROTEINS (BBXs)‐mediated light signal transduction pathway, and highlight still open questions in the field.

光影响着植物生长和发育过程的多个方面，是最重要的环境因素之一。取决于有没有光照，植物会经历暗形态发生或光形态发生。这两个发育进程使得植物生命周期早期的发芽种子成长为健康幼苗。基于CUL4-DDB1的光COP1‐SPA和DET1-CDD E3泛素连接酶复合物在黑暗条件下通过泛素化和降解多个光形态发生促进因子，从而促进植物的暗形态发生。光受体感应光，并将光信号转导到下游的信号通路中，从而起始一系列分子事件以及随后的光形态发生。这些过程由一类组分精确调控，包括各种光受体、E3泛素连接酶和分子水平的转录因子。本文作者综述了目前对于COP1、HY5以及BBXs介导的光信号转导途径的理解，并提出了该领域亟待解决的一些问题。

通讯：许冬清 (http://nx.njau.edu.cn/xdq.pdf)

个人简介：2001-2005年，南京农业大学，学士；2005-2008年，南京农业大学，硕士；2010-2014年，瑞典哥德堡大学，博士；2015-2016年，北京大学，博士后。

doi: https://doi.org/10.1111/nph.16296

Journal: New Phytologist

Published date: October 30, 2019