PlantFAdb: A Resource for Exploring Hundreds of Plant Fatty Acid Structures Synthesized by Thousands of Plants and their Phylogenetic Relationships

First author: John Ohlrogge; Affiliations: Michigan State University (密歇根州立大学): East Lansing, USA

Corresponding author: John Ohlrogge

Over 450 structurally distinct fatty acids are synthesized by plants. We have developed PlantFAdb. org, an internet‐ased database that allows users to search and display fatty acid composition data for over 9000 plants. PlantFAdb includes more than 17,000 data tables from >3000 publications and hundreds of unpublished analyses. A unique feature allows users to easily explore chemotaxonomic relationships (化学分类学关系) between fatty acid structures and plant species by displaying these relationships on dynamic phylogenetic trees. Users can navigate (导航) between order, family, genus and species by clicking on nodes in the tree. The weight % of a selected fatty acid is indicated on phylogenetic trees and clicking in the graph leads to underlying data tables and publications. The display of chemotaxonomy allows users to quickly explore the diversity of plant species that produce each fatty acid, which can provide insights into the evolution of biosynthetic pathways. Fatty acid compositions and other parameters from each plant species have also been compiled from multiple publications on a single page in graphical form. Links provide simple and intuitive (直观的) navigation between fatty acid structures, plant species, data tables and the publications that underlie the datasets. In addition to providing an introduction to this resource this report illustrates examples of insights that can be derived from PlantFAdb. Based on the number of plant families and orders that have not yet been surveyed we estimate that a large number of novel fatty acid structures are still to be discovered in plants.

植物合成超过450种不同结构的脂肪酸。作者开放了在线网站PlantFAdb. org，提供用户搜索和展示超过9000种植物的脂肪酸组成数据。PlantFAdb的数据来自于3000份已发表论文中的17000份数据和数百份未发表的数据。PlantFAdb通过将数据直接展示在一个动态的进化树上，能够让用户比较容易地研究不同脂肪酸结构和植物物种种类之间的化学分类学关系。用户可以直接点击进化树上的分枝来查看目、科、属和种等详细情况。所选脂肪酸占比在进化树上有显示，点击图片会直接链接到数据表和支撑论文。化学分类学显示功能允许用户探索产某个脂肪酸的植物物种多样性，进而帮助理解生物合成通路的演化。每个植物中的脂肪酸组成和其余的一些参数也以图片的形式从发表论文整合到了单个页面上。PlantFAdb提供了脂肪酸结构、植物物种、数据表格和数据论文出处之间简单、直观的链接。除了提供了改数据库网站的简介，本文还简单演示了从PlantFAdb中深度挖掘信息的案例。基于目前植物科、目还未被完整的调查，作者估计还有很多的脂肪酸有待将来进一步的研究去发现。

通讯：John Ohlrogge（https://plantbiology.natsci.msu.edu/directory/john-b-ohlrogge/）

研究方向：植物脂肪酸合成和脂质代谢。

doi: https://doi.org/10.1111/tpj.14102

Journal: the plant journal

First Published: 22 September, 2018

（P.S. 原文下载：链接:https://pan.baidu.com/s/1qFiSsqwlF_7JjmGMbedfhQ  密码:dmu6）