Dynamic Epigenetic Changes during Plant Regeneration

First author: Kyounghee Lee; Affiliations: Sungkyunkwan University (成均馆大学): Suwon, Republic of Korea

Corresponding author: Pil JoonSeo

Plants have the remarkable ability to drive cellular dedifferentiation and regeneration. Changes in epigenetic landscapes accompany the cell fate transition. Notably, modifications of chromatin structure occur primarily during callus formation (愈伤组织形成) via an in vitro tissue culture process and, thus, pluripotent (多能的) callus cells have unique epigenetic signatures. Here, we highlight the latest progress in epigenetic regulation of callus formation in plants, which addresses fundamental questions related to cell fate changes and pluripotency establishment (多能性建立). Global and local modifications of chromatin structure underlie (构成…的基础) callus formation, and the combination and sequence of epigenetic modifications further shape intricate (复杂的) cell fate changes. This review illustrates how a series of chromatin marks change dynamically during callus formation and their biological relevance in plant regeneration.

植物具有细胞去分化和再生的非凡能力。伴随着细胞命运的转变，植物表观组也在发生变化。尤其是通过体外组织培养过程，染色质结构的修饰主要发生在愈伤组织形成时期，因此多能性的愈伤细胞具有独特的表观信号。本文，作者强调了在植物愈伤形成过程中的表观调控所取得的最新研究进展，这解决了细胞命运改变和多能性建立的基础生物学问题。全局或局部的染色质结构修饰构成了愈伤形成的基础，不同表观修饰的组合和顺序进一步塑造了复杂的细胞命运改变。本综述阐述了一系列的染色质标记在愈伤形成过程中的变化及其在植物再生过程中的相关生物学功能。

通讯：Pil JoonSeo (http://www.skku.edu/new_home/industry/faunist/faunist_popup.jsp?d_pub=ASD&d_a1=JAS&d_b1=JAB&d_perfer=227701)

研究方向：植物生物钟与细胞去分化的遗传机理；植物发育过程中的表观重编程。

doi: https://doi.org/10.1016/j.tplants.2017.11.009

Journal: Trends in Plant Science

Published date: March, 2018

（P.S. 欢迎关注微信公众号：微信号Plant_Frontiers）