国际研究进展与参考文献：
| 盘点基因编辑新利器 |
| CRISPR-Cas9技术的局限性促使研究人员寻找替代方法 |
http://news.sciencenet.cn/htmlnews/2016/8/353643.shtm
Beyond CRISPR: A guide to the many other ways to edit a genome
The popular technique has limitations that have sparked searches for alternatives.
http://www.nature.com/news/beyond-crispr-a-guide-to-the-many-other-ways-to-edit-a-genome-1.20388
ReferencesRan, F. A. et al. Nature 520, 186–191 (2015).
Show contextNelson, C. E. et al. Science 351, 403–407 (2016).
Show contextTabebordbar, M. et al. Science 351, 407–411 (2016).
Show contextKim, D. et al. Nature Biotechnol. http://dx.doi.org/10.1038/nbt.3609 (2016).
Show contextKleinstiver, B. P. et al. Nature Biotechnol. http://dx.doi.org/10.1038/nbt.3620 (2016).
Show contextAbudayyeh, O. O. et al. Science 353, aaf5573 (2016).
Show contextKomor, A. C., Kim, Y. B., Packer, M. S., Zuris, J. A. & Liu, D. R. Nature 533, 420–424 (2016).
Show contextNishida, K. et al. Science http://dx.doi.org/10.1126/science.aaf8729 (2016).
Show contextGao, F. et al. Nature Biotechnol. 34, 768–773 (2016).
Show context
PUBMED文献数据库CRISPR-Cas9技术研究论文1722篇分布如下：
数据来源 http://www.pubmedplus.cn/
10.worcester.us 13 篇0.804% 34.state university 7 篇0.433% 37.戴维斯(加州大学戴维斯分校) 7 篇0.433% 39.kettering.us 6 篇0.371% 32.Gersbach CA 15 篇0.928% 04.霍华德·休斯医学研究所 34 篇2.103% 13.劳伦斯伯克利实验室(lbl) 12 篇0.742% 21.美国加州大学圣地亚哥分校 10 篇0.618% 26.威斯康星 - 麦迪逊大学 8 篇0.495% 34.北卡罗来纳大学教堂山分校 7 篇0.433% 37.德克萨斯大学西南医学中心 7 篇0.433% 38.美国德州大学西南医学中心 7 篇0.433% 46.纪念斯隆-凯特琳癌症中心 6 篇0.371% 47.georgia institute of technology and emory university 5 篇0.309% 01.crispr-cas systems 330 篇20.408% 02.clustered regularly interspaced short palindromic repeats 251 篇15.523% 03.genetic engineering 193 篇11.936% 04.base sequence 146 篇9.029% 05.molecular sequence data 115 篇7.112% 06.gene targeting 112 篇6.926% 07.rna, guide 108 篇6.679% 11.crispr-associated proteins 79 篇4.886% 12.endonucleases 77 篇4.762% 13.rna editing 66 篇4.082% 14.gene knockout techniques 64 篇3.958% 15.mutagenesis 54 篇3.340% 16.gene expression regulation 46 篇2.845% 17.genetic vectors 46 篇2.845% 18.hek293 cells 46 篇2.845% 19.genetic therapy 44 篇2.721% 20.genome, human 44 篇2.721% 24.cell line, tumor 36 篇2.226% 25.cells, cultured 36 篇2.226% 26.gene knock-in techniques 35 篇2.165% 28.bacterial proteins 33 篇2.041% 29.deoxyribonucleases 32 篇1.979% 30.dna-binding proteins 30 篇1.855% 31.rna, messenger 30 篇1.855% 32.homologous recombination 29 篇1.793% 34.animals, genetically modified 28 篇1.732% 36.genetic loci 28 篇1.732% 38.dna breaks, double-stranded 27 篇1.670% 39.models, genetic 27 篇1.670% 41.embryonic stem cells 26 篇1.608% 42.mice, inbred c57bl 26 篇1.608% 43.caenorhabditis elegans 25 篇1.546% 44.reproducibility of results 25 篇1.546% 45.transcription factors 25 篇1.546% 46.cell differentiation 24 篇1.484% 47.gene deletion 24 篇1.484% 48.gene expression 24 篇1.484% 49.induced pluripotent stem cells 24 篇1.484% 50.promoter regions, genetic 24 篇1.484% 01.rna, guide 108 篇6.679% 02.crispr-associated proteins 79 篇4.886% 03.endonucleases 77 篇4.762% 05.bacterial proteins 33 篇2.041% 06.deoxyribonucleases 32 篇1.979% 07.dna-binding proteins 30 篇1.855% 08.rna, messenger 30 篇1.855% 查看更多
16.先天性遗传性新生儿疾病和畸形 9 篇0.557% 06.医学生物化学与分子生物学 18 篇1.113%
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