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糖尿病挨冻治疗的知识发现
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信息检索、数据分析、知识发现都是科研人员的必备技能，一旦掌握，事半功倍。
许培扬 知识发现系列博文 http://blog.sciencenet.cn/home.php?mod=space&uid=280034&do=blog&classid=115378&view=me&from=space
科学研究与知识发现 http://blog.sciencenet.cn/home.php?mod=space&uid=280034&do=blog&id=327994
最新研究参考文献：
王凯《自然 医学》：不吃药不打针，挨冻搞定糖尿病？ http://blog.sciencenet.cn/home.php?mod=space&uid=282107&do=blog&id=911648
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A-query: type 2 diabetes mellitus C-query: GLUT4 The B-list contains title words and phrases (terms) that appeared in both the A and the C literature. 442 articles appeared in both literatures and were not included in the process of computing the B-list but can be viewed here. The results of this search are saved under id # 9738 and can be accessed from the start page after you leave this session. There are 829 terms on the current B-list (333 are predicted to be relevant), which is shown ranked according to predicted relevance. The list can be further trimmed down using the filters listed in the left margin. To assess whether there appears to be a biologically significant relationship between the AB and BC literatures for specific B-terms, please select one or more B-terms and then click the button to view the corresponding AB and BC literatures. Use Ctrl to select multiple B-terms.
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http://arrowsmith.psych.uic.edu/cgi-bin/arrowsmith_uic/edit_b.cgi
| type 2 diabetes mellitus | jnk | GLUT4 |
| 1: TRAM1 protect HepG2 cells from palmitate induced insulin resistance through ER stress-JNK pathway. 2015 Add to clipboard 2: Inflammation-induced ROS generation causes pancreatic cell death through modulation of Nrf2-NF-kappaB and SAPK/JNK pathway. 2015 3: Duodenal-Jejunal Bypass Improves Glucose Homeostasis in Association with Decreased Proinflammatory Response and Activation of JNK in the Liver and Adipose Tissue in a T2DM Rat Model. 2014 4: Resolvin D1 reduces ER stress-induced apoptosis and triglyceride accumulation through JNK pathway in HepG2 cells. 2014 5: Compound K protects pancreatic islet cells against apoptosis through inhibition of the AMPK/JNK pathway in type 2 diabetic mice and in MIN6 beta-cells. 2014 6: Common variants in PERK, JNK, BIP and XBP1 genes are associated with the risk of prediabetes or diabetes-related phenotypes in a Chinese population. 2014 7: Hepatitis C virus NS5A protein enhances gluconeogenesis through upregulation of Akt-/JNK-PEPCK signalling pathways. 2014 8: Emerging Role of JNK in Insulin Resistance. 2013 9: [Targeting the stress-responsive JNK/p38-AP1 pathway for therapeutic intervention]. 2012 10: Exercise training improves basal blood glucose metabolism with no changes of cytosolic IKK, JNK activation in skeletal muscle of OLETF rat. 2011 11: Visfatin Is Regulated by Rosiglitazone in Type 2 Diabetes Mellitus and Influenced by NFkappaB and JNK in Human Abdominal Subcutaneous Adipocytes. 2011 12: Design and characterization of a potent and selective dual ATP- and substrate-competitive subnanomolar bidentate c-Jun N-terminal kinase (JNK) inhibitor. 2011 13: Type 2 diabetes is associated with altered NF-kappaB DNA binding activity, JNK phosphorylation, and AMPK phosphorylation in skeletal muscle after LPS. 2011 14: Saturated Fatty Acids Induce c-Src Clustering within Membrane Subdomains, Leading to JNK Activation. 2011 15: Acute oxidative stress can reverse insulin resistance by inactivation of cytoplasmic JNK. 2010 16: Rosiglitazone reduces tau phosphorylation via JNK inhibition in the hippocampus of rats with type 2 diabetes and tau transfected SH-SY5Y cells. 2010 17: Role of the JNK-interacting protein 1/islet brain 1 in cell degeneration in Alzheimer disease and diabetes. 2009
| 1: Rac-1 superactivation triggers insulin-independent GLUT4 translocation that bypasses signalling defects exerted by JNK- and ceramide-induced insulin resistance. 2013 Add to clipboard 2: Serum amyloid A attenuates cellular insulin sensitivity by increasing JNK activity in 3T3-L1 adipocytes. 2009 3: Oleylethanolamide impairs glucose tolerance and inhibits insulin-stimulated glucose uptake in rat adipocytes through p38 and JNK MAPK pathways. 2005 4:JNK and tumor necrosis factor-alpha mediate free fatty acid-induced insulin resistance in 3T3-L1 adipocytes. 2005
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http://arrowsmith.psych.uic.edu/cgi-bin/arrowsmith_uic/show_sentences.cgi
https://blog.sciencenet.cn/blog-280034-911661.html
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