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很麻烦的疾病,看看国际研究如何,有什么好的治疗方法。
一个家族4代39人,因为Alport综合征(遗传性肾炎),已有7人去世,目前12人确诊,还有8人被查出有隐性基因。http://news.sina.com.cn/s/2015-01-08/103531375265.shtml
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2014 64 2012 49 2009 40 2008 39 2013 38 2000 37 2005 36 2010 35 2007 34 1998 34 2003 32 1997 28 1996 28 1993 28 2011 27 2004 27 2002 27 1995 26 2006 25 1994 25 1 2 3 United States 198 Japan 75 Germany 48 Italy 43 France 42 China 41 Australia 38 United Kingdom 36 Canada 27 Finland 19 Netherlands 17 Spain 16 Belgium 15 Cyprus 10 Denmark 10 India 9 Switzerland 7 South Korea 7 Iran 6 Sweden 6 1 2 3 Minneapolis 37 Paris 33 Melbourne 25 Beijing 19 Saint Louis 18 Oulu 16 London 15 Omaha 13 Göttingen 12 Kōbe 12 New York City 11 Nicosia 10 Boston 10 Kansas City 10 Roma 9 Toronto 9 Siena 9 Tokyo 8 Okayama 8 Salt Lake City 7 1 2 3 ...14 Kidney Int 61 Pediatr Nephrol 58 J Am Soc Nephrol 37 Nephrol Dial Transpl 26 Am J Pathol 16 J Biol Chem 16 Hum Mutat 14 Nephrol Dial Transplant 13 Clin Nephrol 13 Am J Hum Genet 13 Genomics 13 Nephron 12 Hum Genet 11 Clin Genet 10 Semin Nephrol 8 Nat Rev Nephrol 7 J Clin Invest 7 Am J Med Genet A 7 Hum Mol Genet 7 Clin J Am Soc Nephrol 6 1 2 3 ...18 Nephritis, Hereditary 798 Syndrome 789 Humans 708 Patients 476 Male 465 Female 417 Genes 398 Collagen 383 Membranes 379 Basement Membrane 370 Mutation 366 membrane 357 collagen 345 Collagen Type IV 345 basement membrane disassembly 330 basement membrane 330 Kidney 302 Adult 271 Glomerular Basement Membrane 233 glomerular basement membrane development 209 1 2 3 ...219 Kashtan C 44 Sado Y 27 Tryggvason K 25 Renieri A 22 Gubler M 21 Zhou J 21 Antignac C 20 Savige J 19 Michael A 19 Miner J 15 Naito I 15 Hudson B 14 Kalluri R 14 Ding J 13 Grünfeld J 13 Gregory M 13 Kleppel M 13 Heidet L 12 Atkin C 12 Hertz J 11 1 2 3 ...180
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