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癌基因本体信息分析

已有 2491 次阅读 2013-9-5 17:10 |个人分类:信息分析|系统分类:科研笔记| 信息

癌基因是指人类或其他动物细胞（以及致癌病毒）固有的一类基因。又称转化基因，它们一旦活化便能促使人或动物的正常细胞发生癌变。http://baike.baidu.com/link?url=ZKbEGlQ7SCGi4qWfm6tnRFbkqTRnPfHSIS27vQfZf8PEIfw9TAE7FhiDPamuthuY

检索策略 oncogene OR cancer gene

检索日期 2013年9月5日17时

分析平台 http://www.pubmedplus.cn/Pubmed/Statistic

分析结果如下：

字段：基因本体1

记录数

占%

01.development 66955 篇16.486%

02.apoptosis 57090 篇14.057%

03.binding 53916 篇13.276%

04.phosphorylation 33395 篇8.223%

05.death 28121 篇6.924%

06.cell cycle 27911 篇6.873%

07.chromosome 24270 篇5.976%

08.cell proliferation 24146 篇5.946%

09.membrane 20075 篇4.943%

10.cell death 18894 篇4.652%

11.extracellular 16331 篇4.021%

12.transduction 15861 篇3.905%

13.intracellular 15643 篇3.852%

14.pathogenesis 14750 篇3.632%

15.nucleus 12310 篇3.031%

16.localization 11634 篇2.865%

17.dna binding 9972 篇2.455%

18.chromatin 9702 篇2.389%

19.reverse transcription 8045 篇1.981%

20.host 8011 篇1.973%

21.kinase activity 7617 篇1.876%

22.mapk 7564 篇1.862%

23.cell surface 7430 篇1.829%

24.behavior 7256 篇1.787%

25.chromosomes 6784 篇1.670%

26.er 6618 篇1.630%

27.secretion 6380 篇1.571%

28.cytoplasm 6056 篇1.491%

29.translation 5763 篇1.419%

30.transmembrane 5230 篇1.288%

31.cell adhesion 5037 篇1.240%

32.homeostasis 5020 篇1.236%

33.extracellular matrix 4667 篇1.149%

34.immune response 4381 篇1.079%

35.transport 4185 篇1.030%

36.mutagenesis 3755 篇0.925%

37.plasma membrane 3658 篇0.901%

38.collagen 3570 篇0.879%

39.protease 3318 篇0.817%

40.membranes 2826 篇0.696%

41.cytoskeleton 2816 篇0.693%

42.cytosol 2335 篇0.575%

43.biosynthesis 2252 篇0.555%

44.endoplasmic reticulum 2118 篇0.522%

45.microtubule 1821 篇0.448%

46.digestion 1630 篇0.401%

47.proteases 1592 篇0.392%

48.pregnancy 1557 篇0.383%

49.protein binding 1124 篇0.277%

50.excretion 439 篇

0.108

字段：基因本体2(细胞组件)

记录数

占%

01.chromosome 33103 篇8.151%

02.intracellular 21842 篇5.378%

03.cell surface 12080 篇2.974%

04.chromatin 11209 篇2.760%

05.plasma membrane 9285 篇2.286%

06.host 8573 篇2.111%

07.endoplasmic reticulum 8286 篇2.040%

08.cytoplasm 8088 篇1.992%

09.cytoskeleton 7993 篇1.968%

10.extracellular matrix 6105 篇1.503%

11.collagen 4579 篇1.127%

12.microtubule 4342 篇1.069%

13.type iii intermediate filament 2601 篇0.640%

14.peroxisome 1536 篇0.378%

15.x chromosome 1487 篇0.366%

16.virion 1382 篇0.340%

17.protein complex 1270 篇0.313%

18.axon 1265 篇0.311%

19.plastoglobule 1063 篇0.262%

20.vacuole 599 篇0.147%

21.nuclear matrix 514 篇0.127%

22.outer membrane 490 篇0.121%

23.m band 349 篇0.086%

24.y chromosome 343 篇0.084%

25.myelin sheath 243 篇0.060%

26.nucleolus organizer region 242 篇0.060%

27.early endosome 216 篇0.053%

28.nadh dehydrogenase complex 187 篇0.046%

29.cell wall 180 篇0.044%

30.a band 110 篇0.027%

31.brush border 91 篇0.022%

32.coated vesicle 73 篇0.018%

33.cytoplasmic mrna processing body 47 篇0.012%

34.z disc 15 篇0.004%

35.cytoplasmic part 13 篇0.003%

36.cell tip 10 篇0.002%

37.sex chromatin 10 篇0.002%

38.trailing edge 6 篇0.001%

39.fact complex 4 篇0.001%

40.i band 4 篇0.001%

41.p granule 4 篇0.001%

42.chromosomal part 3 篇0.001%

43.h zone 2 篇0.000%

44.nuclear dicing body 1 篇0.000%

45.cytoskeletal part 1 篇

0.000

字段：基因本体2(分子功能)

记录数

占%

01.dna binding 37276 篇9.179%

02.rna-directed rna polymerase activity 28463 篇7.008%

03.map kinase activity 18739 篇4.614%

04.protein binding 14973 篇3.687%

05.ethanolamine-phosphate cytidylyltransferase activity 8848 篇2.179%

06.deoxyribodipyrimidine photo-lyase activity 8470 篇2.086%

07.kinase activity 7626 篇1.878%

08.ubiquitin-protein ligase activity 5681 篇1.399%

09.jun kinase activity 5138 篇1.265%

10.insulin-like growth factor receptor binding 5027 篇1.238%

11.protein kinase c activity 3649 篇0.898%

12.interleukin-6 receptor binding 3349 篇0.825%

13.catalytic activity 2520 篇0.621%

14.cyclin-dependent protein kinase activity 2271 篇0.559%

15.taurine-pyruvate aminotransferase activity 2003 篇0.493%

16.interleukin-1 receptor binding 1288 篇0.317%

17.receptor binding 1252 篇0.308%

18.protein serine/threonine phosphatase activity 988 篇0.243%

19.superoxide dismutase activity 562 篇0.138%

20.peroxidase activity 499 篇0.123%

21.template for synthesis of g-rich strand of telomere dna activity 373 篇0.092%

22.gtpase activity 371 篇0.091%

23.phospholipase a2 activity 164 篇0.040%

24.notch binding 150 篇0.037%

25.au-rich element binding 108 篇0.027%

26.nitric oxide binding 80 篇0.020%

27.chloramphenicol o-acetyltransferase activity 70 篇0.017%

28.l-aspartate:2-oxoglutarate aminotransferase activity 68 篇0.017%

29.g-protein coupled adenosine receptor activity 56 篇0.014%

30.cholesterol monooxygenase (side-chain-cleaving) activity 46 篇0.011%

31.lanosterol synthase activity 32 篇0.008%

32.at dna binding 29 篇0.007%

33.electron carrier activity 18 篇0.004%

34.catechol 1,2-dioxygenase activity 10 篇0.002%

35.thymidine phosphorylase activity 8 篇0.002%

36.peptidylglycine monooxygenase activity 1 篇0.000%

37.dimethylargininase activity 1 篇

0.000

字段：基因本体2(生物过程)

记录数

占%

01.biological regulation 139929 篇34.455%

02.growth 111394 篇27.429%

03.biosynthetic process 94862 篇23.358%

04.transcription, dna-dependent 89965 篇22.152%

05.developmental process 73985 篇18.217%

06.signaling 68733 篇16.924%

07.apoptosis 67205 篇16.548%

08.signal transduction 60160 篇14.813%

09.regulation of cell cycle 57545 篇14.169%

10.cell cycle 39322 篇9.682%

11.cell growth 20220 篇4.979%

12.cytolysis 13241 篇3.260%

13.localization 12297 篇3.028%

14.catabolic process 11886 篇2.927%

15.translation 11835 篇2.914%

16.angiogenesis 10884 篇2.680%

17.behavior 10601 篇2.610%

18.rna interference 9749 篇2.401%

19.aging 6797 篇1.674%

20.cell cycle arrest 6125 篇1.508%

21.s phase 5963 篇1.468%

22.homeostatic process 5650 篇1.391%

23.plant-type hypersensitive response 3888 篇0.957%

24.cell development 3537 篇0.871%

25.anatomical structure morphogenesis 2779 篇0.684%

26.hypersensitivity 2466 篇0.607%

27.embryo development 2393 篇0.589%

28.proteolysis 1834 篇0.452%

29.m phase 1692 篇0.417%

30.endocytosis 1385 篇0.341%

31.t cell activation 1323 篇0.326%

32.cellular localization 994 篇0.245%

33.post-translational protein modification 904 篇0.223%

34.b cell differentiation 897 篇0.221%

35.female pregnancy 888 篇0.219%

36.protein folding 850 篇0.209%

37.t cell differentiation 819 篇0.202%

38.protein phosphorylation 803 篇0.198%

39.protein catabolic process 772 篇0.190%

40.t cell proliferation 598 篇0.147%

41.v(d)j recombination 369 篇0.091%

42.b cell activation 255 篇0.063%

43.notch signaling pathway 218 篇0.054%

44.b cell proliferation 200 篇0.049%

45.b cell apoptosis 75 篇0.018%

46.t cell migration 43 篇0.011%

47.turning behavior 22 篇0.005%

48.nitric oxide homeostasis 1 篇0.000%

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