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ceramide-1-phosphate转运蛋白与癌症和炎症研究的知识发现
Nature重要发现:将癌症、炎症一网打尽
在癌症研究中,发现一个在癌症中起作用的新蛋白,就如同找到了一个宝库的钥匙和藏宝图:沿着线索追踪,最终就会获得丰厚的回报。发表在《自然》(Nature)杂志上的一项新研究,发现了一个称之为CPTP(ceramide-1-phosphate转运蛋白)的新型蛋白,为我们带来了这一希望。该研究发现可能最终促使开发出治疗各种癌症和炎症、血栓形成等其他疾病的新药物。http://www.ebiotrade.com/newsf/2013-8/201381104007575.htm
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A-query: ceramide-1-phosphate transfer protein C-query: cancer and inflammation The B-list contains title words and phrases (terms) that appeared in both the A and the C literature. 1 articles appeared in both literatures and were not included in the process of computing the B-list but can be viewed here. The results of this search are saved under id # 6072 and can be accessed from the start page after you leave this session. There are 36 terms on the current B-list (发现13个重要的相关知识概念 are predicted to be relevant), which is shown ranked according to predicted relevance. The list can be further trimmed down using the filters listed in the left margin. To assess whether there appears to be a biologically significant relationship between the AB and BC literatures for specific B-terms, please select one or more B-terms and then click the button to view the corresponding AB and BC literatures. Use Ctrl to select multiple B-terms.
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http://arrowsmith.psych.uic.edu/cgi-bin/arrowsmith_uic/edit_b.cgi?refresh=T&ID=6072
job id # 6072 started Fri Aug 2 01:20:19 2013
Max_citations: 50000
Stoplist: /var/www/arrowsmith_uic/data/stopwords_pubmed
Ngram_max: 3
A_query_raw: ceramide-1-phosphate transfer protein Fri Aug 2 01:20:25 2013
A query = ceramide-1-phosphate transfer protein started Fri Aug 2 01:20:26 2013
A query resulted in 4 titles
C_query_raw: ceramide-1-phosphate transfer protein Fri Aug 2 01:20:28 2013
C: ceramide-1-phosphate transfer protein 4
A: pubmed_query_A 4
AC: ( ceramide-1-phosphate transfer protein ) AND ( ceramide-1-phosphate transfer protein ) 4
C_query_raw: cancer and inflammation Fri Aug 2 01:21:28 2013
C: cancer and inflammation 44299
A: pubmed_query_A 4
AC: ( ceramide-1-phosphate transfer protein ) AND ( cancer and inflammation ) 1
C_query_raw: cancer and inflammation Fri Aug 2 01:21:31 2013
C: cancer and inflammation 44299
A: pubmed_query_A 4
AC: ( ceramide-1-phosphate transfer protein ) AND ( cancer and inflammation ) 1
C query = cancer and inflammation started Fri Aug 2 01:21:32 2013
C query resulted in 44299 titles
A AND C query resulted in 1 titles
36 B-terms ready on Fri Aug 2 01:22:22 2013
B-list on Fri Aug 2 01:25:53 2013
1 sp1
2 ceramide
3 bioactive sphingolipid
4 cathepsin
5 ceramide kinase
6 sp3
7 kinase
8 sphingolipid
9 protein gene
10 bioactive
11 1-phosphate
12 ceramide 1-phosphate
13 cathepsin d
知识发现示例:请查阅AC研究论文或BC研究论文,是否对你有所启发和参考意义。
ceramide-1-phosphate transfer ... | cathepsin | cancer and inflammation |
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http://arrowsmith.psych.uic.edu/cgi-bin/arrowsmith_uic/show_sentences.cgi
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