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生物化学、遗传学、分子生物学最热门论文25篇（2012年1-3月）
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January to March 2012
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Hallmarks of Cancer: The Next Generation • Review article Cell, Volume 144, Issue 5, March 2011, Pages 646-674 Hanahan, D.; Weinberg, Robert A. <!-- Bookmark article</a> -->  Cited by SciVerse Scopus (741) |
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Resveratrol Ameliorates Aging-Related Metabolic Phenotypes by Inhibiting cAMP Phosphodiesterases • Article Cell, Volume 148, Issue 3, February 2012, Pages 421-433 Park, S.J.; Ahmad, F.; Philp, A.; Baar, K.; Williams, T.; Luo, H.; Ke, H.; Rehmann, H.; Taussig, R.; Brown, Alexandra L.; Kim, Myung K.; Beaven, Michael A.; Burgin, Alex B.; Manganiello, V.; Chung, Jay H. <!-- Bookmark article</a> --> Cited by SciVerse Scopus (1) |
| 3. |
EMT and Dissemination Precede Pancreatic Tumor Formation • Article Cell, Volume 148, Issue 1-2, January 2012, Pages 349-361 Rhim, Andrew D.; Mirek, Emily T.; Aiello, Nicole M.; Maitra, A.; Bailey, Jennifer M.; McAllister, F.; Reichert, M.; Beatty, Gregory L.; Rustgi, Anil K.; Vonderheide, Robert H.; Leach, Steven D.; Stanger, Ben Z. <!-- Bookmark article</a> --> Cited by SciVerse Scopus (3) |
| 4. |
Single-Cell Exome Sequencing and Monoclonal Evolution of a JAK2-Negative Myeloproliferative Neoplasm • Article Cell, Volume 148, Issue 5, March 2012, Pages 873-885 Hou, Y.; Song, L.; Zhu, P.; Zhang, B.; Tao, Y.; Xu, X.; Li, F.; Wu, K.; Liang, J.; Shao, D.; Wu, H.; Ye, X.; Ye, C.; Wu, R.; Jian, M.; Chen, Y.; Xie, W.; Zhang, R.; Chen, L.; Liu, X.; Yao, X.; Zheng, H.; Yu, C.; Li, Q.; Gong, Z.; Mao, M.; Yang, X.; Y <!-- Bookmark article</a> --> Cited by SciVerse Scopus (1) |
| 5. |
Generation of Chimeric Rhesus Monkeys • Article Cell, Volume 148, Issue 1-2, January 2012, Pages 285-295 Tachibana, M.; Sparman, M.; Ramsey, C.; Ma, H.; Lee, H.S.; Penedo, Maria Cecilia T.; Mitalipov, S. <!-- Bookmark article</a> --> Cited by SciVerse Scopus (2) |
| 6. |
Extensive Promoter-Centered Chromatin Interactions Provide a Topological Basis for Transcription Regulation • Article Cell, Volume 148, Issue 1-2, January 2012, Pages 84-98 Li, G.; Ruan, X.; Auerbach, Raymond K.; Sandhu, K.; Zheng, M.; Wang, P.; Poh, H.; Goh, Y.; Lim, J.; Zhang, J.; Sim, H.; Peh, S.; Mulawadi, F.; Ong, C.; Orlov, Yuriy L.; Hong, S.; Zhang, Z.; Landt, S.; Raha, D.; Euskirchen, G.; Wei, C.L.; Ge, W.; Wang <!-- Bookmark article</a> --> |
| 7. |
The Hallmarks of Cancer • Review article Cell, Volume 100, Issue 1, January 2000, Pages 57-70 Hanahan, D.; Weinberg, R.A. <!-- Bookmark article</a> --> Cited by SciVerse Scopus (9908) |
| 8. |
Three-Dimensional Folding and Functional Organization Principles of the Drosophila Genome • Article Cell, Volume 148, Issue 3, February 2012, Pages 458-472 Sexton, T.; Yaffe, E.; Kenigsberg, E.; Bantignies, F.; Leblanc, B.; Hoichman, M.; Parrinello, H.; Tanay, A.; Cavalli, G. <!-- Bookmark article</a> --> Cited by SciVerse Scopus (2) |
| 9. |
Glycine Decarboxylase Activity Drives Non-Small Cell Lung Cancer Tumor-Initiating Cells and Tumorigenesis • Article Cell, Volume 148, Issue 1-2, January 2012, Pages 259-272 Zhang, W.; Shyh-Chang, N.; Yang, H.; Rai, A.; Umashankar, S.; Ma, S.; Soh, B.; Sun, L.; Tai, B.; Nga, M.; Bhakoo, K.; Jayapal, S.; Nichane, M.; Yu, Q.; Ahmed, Dokeu A.; Tan, C.; Sing, W.; Tam, J.; Thirugananam, A.; Noghabi, M.; Huei Pang, Y.; Ang, H. <!-- Bookmark article</a> --> Cited by SciVerse Scopus (1) |
| 10. |
Hypoxia-Inducible Factors in Physiology and Medicine • Review article Cell, Volume 148, Issue 3, February 2012, Pages 399-408 Semenza, Gregg L. <!-- Bookmark article</a> --> Cited by SciVerse Scopus (2) |
| 11. |
Comprehensive Genome-wide Protein-DNA Interactions Detected at Single-Nucleotide Resolution • Article Cell, Volume 147, Issue 6, December 2011, Pages 1408-1419 Rhee, H.; Pugh, B. <!-- Bookmark article</a> --> Cited by SciVerse Scopus (6) |
| 12. |
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors • Article Cell, Volume 126, Issue 4, August 2006, Pages 663-676 Takahashi, K.; Yamanaka, S. <!-- Bookmark article</a> --> Cited by SciVerse Scopus (2939) |
| 13. |
Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations • Article Cell, Volume 148, Issue 1-2, January 2012, Pages 59-71 Rausch, T.; Jones, David T.W.; Zapatka, M.; Stutz, Adrian M.; Zichner, T.; Weischenfeldt, J.; Jager, N.; Remke, M.; Shih, D.; Northcott, Paul A.; Pfaff, E.; Tica, J.; Wang, Q.; Massimi, L.; Witt, H.; Bender, S.; Pleier, S.; Cin, H.; Hawkins, C.; Beck <!-- Bookmark article</a> --> Cited by SciVerse Scopus (2) |
| 14. |
Regional Neural Activation Defines a Gateway for Autoreactive T Cells to Cross the Blood-Brain Barrier • Article Cell, Volume 148, Issue 3, February 2012, Pages 447-457 Arima, Y.; Harada, M.; Kamimura, D.; Park, J.H.; Kawano, F.; Yull, Fiona E.; Kawamoto, T.; Iwakura, Y.; Betz, Ulrich A.K.; Marquez, G.; Blackwell, Timothy S.; Ohira, Y.; Hirano, T.; Murakami, M. <!-- Bookmark article</a> --> Cited by SciVerse Scopus (1) |
| 15. |
The Mitochondrial Phosphatase PGAM5 Functions at the Convergence Point of Multiple Necrotic Death Pathways • Article Cell, Volume 148, Issue 1-2, January 2012, Pages 228-243 Wang, Z.; Jiang, H.; Chen, S.; Du, F.; Wang, X. <!-- Bookmark article</a> --> Cited by SciVerse Scopus (3) |
| 16. |
Single-Cell Exome Sequencing Reveals Single-Nucleotide Mutation Characteristics of a Kidney Tumor • Article Cell, Volume 148, Issue 5, March 2012, Pages 886-895 Xu, X.; Hou, Y.; Yin, X.; Bao, L.; Tang, A.; Song, L.; Li, F.; Tsang, S.; Wu, K.; Wu, H.; He, W.; Zeng, L.; Xing, M.; Wu, R.; Jiang, H.; Liu, X.; Cao, D.; Guo, G.; Hu, X.; Gui, Y.; Li, Z.; Xie, W.; Sun, X.; Shi, M.; Cai, Z.; Wang, B.; Zhong, M.; Li, <!-- Bookmark article</a> --> Cited by SciVerse Scopus (3) |
| 17. |
Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase • Article Cell, Volume 148, Issue 1-2, January 2012, Pages 213-227 Sun, L.; Wang, H.; Wang, Z.; He, S.; Chen, S.; Liao, D.; Wang, L.; Yan, J.; Liu, W.; Lei, X.; Wang, X. <!-- Bookmark article</a> --> Cited by SciVerse Scopus (3) |
| 18. |
TAK1 Inhibition Promotes Apoptosis in KRAS-Dependent Colon Cancers • Article Cell, Volume 148, Issue 4, February 2012, Pages 639-650 Singh, A.; Sweeney, Michael F.; Yu, M.; Burger, A.; Greninger, P.; Benes, C.; Haber, Daniel A.; Settleman, J. <!-- Bookmark article</a> --> |
| 19. |
Slug and Sox9 Cooperatively Determine the Mammary Stem Cell State • Article Cell, Volume 148, Issue 5, March 2012, Pages 1015-1028 Guo, W.; Keckesova, Z.; Donaher, J.; Shibue, T.; Tischler, V.; Reinhardt, F.; Itzkovitz, S.; Noske, A.; Zurrer-Hardi, U.; Bell, G.; Tam, W.; Mani, Sendurai A.; van Oudenaarden, A.; Weinberg, Robert A. <!-- Bookmark article</a> --> |
| 20. |
Systemic Elevation of PTEN Induces a Tumor-Suppressive Metabolic State • Article Cell, Volume 149, Issue 1, March 2012, Pages 49-62 Garcia-Cao, I.; Song, M.; Hobbs, Robin M.; Laurent, G.; Giorgi, C.; de Boer, Vincent C.J.; Anastasiou, D.; Ito, K.; Sasaki, Atsuo T.; Rameh, L.; Carracedo, A.; Vander Heiden, Matthew G.; Cantley, Lewis C.; Pinton, P.; Haigis, Marcia C.; Pandolfi, P. <!-- Bookmark article</a> --> |
| 21. |
Tumor Metastasis: Molecular Insights and Evolving Paradigms • Review article Cell, Volume 147, Issue 2, October 2011, Pages 275-292 Valastyan, S.; Weinberg, Robert A. <!-- Bookmark article</a> --> Cited by SciVerse Scopus (8) |
| 22. |
The Genetic Basis for Cancer Treatment Decisions • Review article Cell, Volume 148, Issue 3, February 2012, Pages 409-420 Dancey, Janet E.; Bedard, Philippe L.; Onetto, N.; Hudson, Thomas J. <!-- Bookmark article</a> --> Cited by SciVerse Scopus (1) |
| 23. |
A Differentiation Checkpoint Limits Hematopoietic Stem Cell Self-Renewal in Response to DNA Damage • Article Cell, Volume 148, Issue 5, March 2012, Pages 1001-1014 Wang, J.; Sun, Q.; Morita, Y.; Jiang, H.; Grosz, A.; Lechel, A.; Hildner, K.; Guachalla, L.; Gompf, A.; Hartmann, D.; Schambach, A.; Wuestefeld, T.; Dauch, D.; Schrezenmeier, H.; Hofmann, W.K.; Nakauchi, H.; Ju, Z.; Kestler, Hans A.; Zender, L.; Rudo <!-- Bookmark article</a> --> Cited by SciVerse Scopus (1) |
| 24. |
Membrane Tension Maintains Cell Polarity by Confining Signals to the Leading Edge during Neutrophil Migration • Article Cell, Volume 148, Issue 1-2, January 2012, Pages 175-188 Houk, Andrew R.; Jilkine, A.; Mejean, Cecile O.; Boltyanskiy, R.; Dufresne, Eric R.; Angenent, Sigurd B.; Altschuler, Steven J.; Wu, Lani F.; Weiner, Orion D. <!-- Bookmark article</a> --> Cited by SciVerse Scopus (5) |
| 25. |
Conserved Function of lincRNAs in Vertebrate Embryonic Development despite Rapid Sequence Evolution • Article Cell, Volume 147, Issue 7, December 2011, Pages 1537-1550 Ulitsky, I.; Shkumatava, A.; Jan, Calvin H.; Sive, H.; Bartel, David P. <!-- Bookmark article</a> --> Cited by SciVerse Scopus (1) |
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