原创博文

 

    过继免疫是把致敏淋巴细胞（具有特异免疫力的）或致敏淋巴细胞的产物（例如转移因子和免疫核糖核酸等）输给细胞免疫功能低下者（如肿瘤病人），使其获得抗肿瘤免疫力。过继免疫或继承性免疫犹如继承他人的财产而获得财力，它是用来治疗肿瘤的一种免疫疗法。基于肿瘤的发生、发展和预后与机体免疫功能，尤其是细胞免疫功能关系密切，1985年美国国家癌症研究委员会将癌症的免疫疗法确立为继外科手术、放射疗法和化学药物疗法之后的第四种疗法。过继免疫即是肿瘤生物疗法中的一种。

 

知识发现平台  http://arrowsmith.psych.uic.edu/cgi-bin/arrowsmith_uic/edit_b.cgi

 

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A-query: immune surveillance C-query: adoptive immunotherapy The B-list contains title words and phrases (terms) that appeared in both the A and the C literature. 87 articles appeared in both literatures and were not included in the process of computing the B-list but can be viewed here. The results of this search are saved under id # 9005 and can be accessed from the start page after you leave this session. There are 1713 terms on the current B-list (发现1024 个过继免疫治疗疾病的文献隐含知识概念，对相关科研工作有参考价值are predicted to be relevant), which is shown ranked according to predicted relevance. The list can be further trimmed down using the filters listed in the left margin. To assess whether there appears to be a biologically significant relationship between the AB and BC literatures for specific B-terms, please select one or more B-terms and then click the button to view the corresponding AB and BC literatures. Use Ctrl to select multiple B-terms.

 

 

 

AC: ( immune surveillance ) AND ( adoptive immunotherapy ) 87

C query = adoptive immunotherapy started Wed Dec 14 18:09:53 2011
C query resulted in 7454 titles
A AND C query resulted in 87 titles
9091 B-terms ready on Wed Dec 14 18:11:31 2011

Sem_filter:
Disorders
1713 B-terms left after filter executed Wed Dec 14 18:16:36 2011

前300个知识点

B-list on Wed Dec 14 18:21:10 2011
1 gene therapy cancer
2 cd25 regulatory t
3 dendritic cell cancer
4 transplant lymphoproliferative disease
5 transplant lymphoproliferative disorder
6 memory cd8 t
7 chronic hepatitis b
8 melanoma associated antigen
9 memory cd8
10 cytomegalovirus disease
11 cd4 cd8 t
12 c virus infection
13 based immunotherapy cancer
14 active ebv infection
15 barr virus infection
16 bowel transplantation
17 experimental autoimmune uveitis
18 hiv-1 infection
19 cytolytic t
20 hepatocellular carcinoma cell
21 b16 melanoma
22 immunotherapy malignant glioma
23 posttransplant lymphoproliferative disease
24 posttransplant lymphoproliferative disorder
25 memory cd4
26 tumor infiltrating lymphocyte
27 cell mediated cytotoxicity
28 cell lung carcinoma
29 cd8 cytotoxic t
30 cd8 cytotoxic
31 gammadelta t
32 cutaneous melanoma
33 hepatitis c
34 memory t cell
35 killer activity
36 patient hepatocellular carcinoma
37 murine melanoma
38 cytotoxic lymphocyte
39 natural killer activity
40 cell hepatocellular carcinoma
41 immunotherapy malignant
42 carcinoma xenograft
43 experimental tumor metastasis
44 glioma model
45 prostate cancer immunotherapy
46 collagen induced arthritis
47 b16
48 immunotherapy cancer
49 human hepatocellular carcinoma
50 t cell memory
51 tumoricidal activity
52 cmv infection
53 antiretroviral therapy
54 cd8 t
55 restricted cytotoxic
56 antigen recognized t
57 tumor immunology
58 intraocular tumor
59 aml
60 autoreactive t
61 syngeneic tumor
62 ebv infection
63 severe combined immunodeficiency
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65 cancer immunotherapy
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69 vaccination prostate cancer
70 killer cell activity
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73 immunotherapy pancreatic cancer
74 hepatocellular carcinoma a
75 target cancer immunotherapy
76 generation cytotoxic
77 organ transplant
78 natural killer t
79 combined immunodeficiency
80 skin cancer
81 specific cd8 t
82 leukemia allogeneic bone
83 therapy cytomegalovirus
84 therapy hiv
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86 cell lung cancer
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88 b virus infection
89 cellular cytotoxicity
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92 murine fibrosarcoma
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94 transfer diabetes
95 vaccine melanoma
96 immunotherapy malignancy
97 associated lymphoproliferative disorder
98 activated t
99 renal cell carcinoma
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101 anti tumor necrosis
102 immunotherapy melanoma
103 lung cancer cell
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105 colorectal cancer a
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141 adoptive transfer diabetes
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147 cross priming cytotoxic
148 necrosis factor receptor
149 restricted cytotoxic t
150 cytotoxicity cytokine
151 metastatic malignant
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154 cell carcinoma a
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160 memory t
161 uveal melanoma
162 human colorectal carcinoma
163 cholangiocarcinoma
164 lymphocytic choriomeningitis
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166 recombinant hepatitis b
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168 killer cytotoxicity
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183 pd-1
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215 immunopathogenesis human immunodeficiency
216 pancreatic adenocarcinoma
217 tumor associated antigen
218 mammary adenocarcinoma
219 effector t cell
220 head neck cancer
221 cancer immunology
222 autoimmune encephalomyelitis
223 lymphocytic leukaemia
224 partially mismatched related
225 malignancy vivo gene
226 immunotherapy malignancy vivo
227 carcinoma head neck
228 cytokine cancer
229 immunity cancer
230 tumor microenvironment immune
231 killer cell tumor
232 memory t lymphocyte
233 cell cytotoxicity
234 hiv disease
235 myelodysplastic
236 tumor targeting
237 immunodeficient
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239 recurrent glioblastoma
240 t lymphocyte activation
241 specific memory cd8
242 cell autoimmunity
243 necrosis factor alpha
244 breast cancer cell
245 murine tumor
246 laryngeal cancer
247 murine colon carcinoma
248 autoimmunity
249 target cancer
250 advanced lung cancer
251 human papilloma
252 influenza a
253 tumor infiltrating dendritic
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255 effector cd8 t
256 hepatocellular carcinoma patient
257 mechanism tumor immune
258 t cell leukemia
259 tumor bearing mice
260 associated lymphoma
261 mismatched related donor
262 activity nk cell
263 targeted therapy
264 cytotoxic response
265 infection immunocompromised
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270 cross priming
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272 cell carcinoma immunotherapy
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292 anti cd4 monoclonal
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298 lymphoproliferative disorder
299 immunogenic tumor
300 antiphospholipid syndrome